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Osteoblasts : morphology, functions and clinical implications /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Science Publishers,
[2013]
|
| Colección: | Cell biology research progress.
Muscular system--anatomy, functions, and injuries series. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 050 | 0 | 0 | |a QP88.2 |
| 060 | 4 | |a WE200 |b .O87 2013 | |
| 072 | 7 | |a MED |x 075000 |2 bisacsh | |
| 072 | 7 | |a SCI |x 036000 |2 bisacsh | |
| 082 | 0 | 0 | |a 612.7/5 |2 23 |
| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Osteoblasts : |b morphology, functions and clinical implications / |c Hugo Scheurer, editor. |
| 264 | 1 | |a New York : |b Nova Science Publishers, |c [2013] | |
| 264 | 4 | |c ©2013 | |
| 300 | |a 1 online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online |b cr |2 rdacarrier | ||
| 490 | 1 | |a Cell biology research progress | |
| 490 | 1 | |a Muscularsystem- anatomy, functions and injuries | |
| 500 | |a "Nova biomedical "--Cover. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | |a Description based on print version record. | ||
| 505 | 0 | |a Intro -- OSTEOBLASTS -- OSTEOBLASTS -- Contents -- Preface -- Osteoblasts under Mechanical Strain -- Abstract -- Abbreviations -- 1. Introduction -- 1.1. Bone Tissue Cellular Structure -- 1.2. Osteoblasts -- 1.2.1. Osteoblast Origin and Life Cycle -- 1.2.2. Osteoblast Function -- 1.2.3. Growth Factor and Hormone Effects on Osteoblasts -- 1.3. Runx2 Transcription Factor in Bone Biology -- 1.3.1. Runx2 in Osteoblast Differentiation -- 1.3.2. Structure of Runx2 Gene -- 1.3.3. Runx2 Expression -- 2. Bone Remodeling -- 2.1. Regulation of Bone Remodeling -- 2.2. The Role of the RANK / RANKL / OPG System in Bone Remodeling -- 2.3. Bone Remodeling Pathophysiology -- 3. Mechanotransduction -- 3.1. Bone Remodeling and Mechanotransduction -- 3.2. Runx2 in Mechanotransduction -- 3.3. Nuclear Factor Î#x9A;appa B (NF-κÎ#x92;) Transcription Factor in Mechanotransduction -- 3.4. Polycystins in Mechanotransduction -- 3.5. Model Systems for the Study of Mechanotransduction in Osteoblasts -- 3.6. The Role of Mechanotransduction in Bone Disease -- 3.7. Mechanical Stimulation as a Therapeutic Strategy against Bone Disease -- Conclusion -- References -- From Stem Cells to Osteoblast: Therapeutic Potential for Bone Tissue Engineering -- Abstract -- Introduction -- Mesenchymal Stem Cells -- Differentiation of MSC into Osteoblast -- Role of Growth Factors and Transcription Factors in Osteoblast Differentiation -- Role of Transcription Factor in Differentiation of Osteoblast -- Scaffolds -- Natural Scaffolds: Extracellular Matrix -- Glycosaminoglycans (GAGs) -- Chitosan Scaffold -- Tripolymer Scaffolds -- References -- Osteoblast Functions and their Role in Skeletal Bone Diseases -- Abstract -- Introduction -- Osteoblast Lineage and Differentiation -- Transcription Factors, Signaling Proteins and Osteoblast Differentiation -- Osteoblast Migration -- Osteoblasts and Bone Diseases. | |
| 505 | 8 | |a Osteoporosis -- Osteoarthritis -- Osteogenesis Imperfecta -- Van Buchem Disease and Sclerosteosis -- Oculodentodigital Dysplasia -- Camurati-Engelmann Disease -- Cleidocranial Dysplaysia -- Osteoblastic Bone Metastasis -- Acknowledgment -- References -- Osteoblast Differentiation and Related Diseases -- Abstract -- Introduction -- A. Transcription Factors Regulating Osteoblast Differentiation -- RUNX2 -- TWIST1 -- MSX1 and MSX2 -- SP7/Osterix -- β-Catenin -- ATF4 -- FoxO1 -- B. Diseases Associated with Osteogenic Transcription Factors -- Cleidocranial Dysplasia (CCD) -- Saethre Chotzen Syndrome (SCS) -- Boston-Type Craniosynostosis -- Non-Collagenous Osteogenesis Imperfecta Caused by SP7/OSX Mutation -- Coffin-Lowry Syndrome (CLS) -- Neurofibromatosis Type I -- Conclusion -- References -- BMP and Osteoblastogenesis Inhibitors -- Abstract -- Bone Morphogenetic Proteins -- BMP-Smad Signaling -- Extracellular Inhibitor -- Cytomembrane Inhibitors -- Intracellular Inhibitors -- Nuclear Inhibitors, Which Interact with Runx2 or Osx -- MicroRNAs -- Prospect for Future Therapy -- References -- The Effect of Molecular and Biochemical Differentiation Agentson Bone Formation -- Abstract -- Introduction -- Osteoblast Differentiation and Inducer Materials -- Standard Medium for Osteogenic Cultures -- Medium Supplements -- Ascorbic Acid -- 1. The Effect of Ascorobic Acid on Osteoclast Formation -- 2. The Effect of Ascorbic Acid on Osteoblast Formation -- B-Glycerophosphate (BGP) -- Dexamethasone (Dex) -- Vitamin D3 -- Bone Morphogenic Protein 2(BMP-2) -- Collagen I and Vetronectin -- Conclusion and Further Remarks -- References -- Evaluation of Characteristics of Osteoblasts and Factors Relatedto Osteoblastic Differentiation and Mineralization -- Abstract -- Introduction -- Characteristics of Osteblast -- Bone Morphogenetic Protein (BMP) -- Various Agents. | |
| 505 | 8 | |a Laboratory Experiments -- (1) Cellular Proliferation -- (2) Alkaline Phosphatase Activity Assays (ALP) -- (3) Mineralization Assay -- Conclusion -- References -- Index. | |
| 546 | |a English. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Osteoclasts. | |
| 650 | 0 | |a Bone resorption. | |
| 650 | 0 | |a Bones |x Diseases. | |
| 650 | 2 | |a Osteoclasts | |
| 650 | 2 | |a Bone Resorption | |
| 650 | 2 | |a Bone Diseases | |
| 650 | 6 | |a Ostéoclastes. | |
| 650 | 6 | |a Os |x Maladies. | |
| 650 | 6 | |a Résorption osseuse. | |
| 650 | 7 | |a MEDICAL |x Physiology. |2 bisacsh | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Human Anatomy & Physiology. |2 bisacsh | |
| 650 | 7 | |a Bone resorption |2 fast | |
| 650 | 7 | |a Bones |x Diseases |2 fast | |
| 650 | 7 | |a Osteoclasts |2 fast | |
| 700 | 1 | |a Scheurer, Hugo. | |
| 776 | 0 | 8 | |i Print version: |t Osteoblasts |d New York : Nova Science Publishers, [2013] |z 9781624178061 |w (DLC) 2012955913 |
| 830 | 0 | |a Cell biology research progress. | |
| 830 | 0 | |a Muscular system--anatomy, functions, and injuries series. | |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=3020631 |z Texto completo |
| 938 | |a YBP Library Services |b YANK |n 10404714 | ||
| 938 | |a EBSCOhost |b EBSC |n 561632 | ||
| 938 | |a ebrary |b EBRY |n ebr10678036 | ||
| 938 | |a EBL - Ebook Library |b EBLB |n EBL3020631 | ||
| 994 | |a 92 |b IZTAP | ||