Randomized phase II cancer clinical trials /

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In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials....

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Jung, Sin-Ho
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken : CRC Press, 2013.
Colección:Chapman & Hall/CRC biostatistics series.
Temas:
Clinical trials > Statistical methods.
Cancer > Research > Statistical methods.
Statistics.
Neoplasms > therapy
Clinical Trials, Phase II as Topic
Randomized Controlled Trials as Topic
Research Design
Statistics as Topic
Études cliniques > Méthodes statistiques.
Cancer > Recherche > Méthodes statistiques.
Statistiques.
Statistique.
statistics.
HEALTH & FITNESS > Diseases > Cancer.
MEDICAL > Oncology.
Statistics
Cancer > Research > Statistical methods
Clinical trials > Statistical methods
Acceso en línea:Texto completo
Descripción
Sumario:In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials. To rectify these problems, oncologists and biostatisticians have begun to use a randomized phase II trial that compares an experimental therapy with a prospective control therapy.
Descripción Física:1 online resource (236 pages).
Bibliografía:Includes bibliographical references.
ISBN:9781439871867
1439871868
143987185X
9781439871850

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