Cargando…
The clinibook : clinical gene transfer : state of the art /
This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory is...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Paris :
EDP Sciences,
2012.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 a 4500 | ||
|---|---|---|---|
| 001 | EBOOKCENTRAL_ocn834607434 | ||
| 003 | OCoLC | ||
| 005 | 20240329122006.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 130313s2012 fr a ob 001 0 eng d | ||
| 040 | |a E7B |b eng |e pn |c E7B |d OCLCQ |d OCLCO |d N$T |d OCLCF |d YDXCP |d EBLCP |d OCLCQ |d DEBSZ |d OCLCQ |d AZK |d COCUF |d AGLDB |d MOR |d PIFAG |d MERUC |d OCLCQ |d ZCU |d U3W |d STF |d WRM |d VTS |d NRAMU |d EZ9 |d ICG |d VT2 |d INT |d OCLCO |d OCLCQ |d WYU |d OCLCA |d OCLCQ |d DKC |d OCLCO |d OCLCQ |d UX1 |d OCLCQ |d OCLCA |d UKCRE |d VLY |d AJS |d OCLCO |d OCL |d DEGRU |d OCLCQ |d OCLCO |d OCLCL |d OCLCQ | ||
| 019 | |a 922991221 |a 961491120 |a 962627039 |a 975212430 |a 975242971 |a 1018055990 |a 1043623299 |a 1063935609 |a 1065945617 |a 1081241018 |a 1086939965 |a 1153495797 |a 1162051070 |a 1228550659 |a 1241931823 |a 1290040162 |a 1297159145 |a 1297621693 |a 1300548444 | ||
| 020 | |a 9782842542375 |q (electronic bk.) | ||
| 020 | |a 2842542371 |q (electronic bk.) | ||
| 020 | |a 9782842542375 |q (e-book) | ||
| 020 | |a 2842541715 | ||
| 020 | |a 9782842541712 | ||
| 020 | |z 9782842541712 | ||
| 020 | |a 1299276822 | ||
| 020 | |a 9781299276826 | ||
| 029 | 1 | |a AU@ |b 000053011958 | |
| 029 | 1 | |a DEBBG |b BV043094835 | |
| 029 | 1 | |a DEBBG |b BV044098134 | |
| 029 | 1 | |a DEBSZ |b 421265396 | |
| 029 | 1 | |a DEBSZ |b 456618848 | |
| 029 | 1 | |a NZ1 |b 15025369 | |
| 029 | 1 | |a AU@ |b 000066749641 | |
| 035 | |a (OCoLC)834607434 |z (OCoLC)922991221 |z (OCoLC)961491120 |z (OCoLC)962627039 |z (OCoLC)975212430 |z (OCoLC)975242971 |z (OCoLC)1018055990 |z (OCoLC)1043623299 |z (OCoLC)1063935609 |z (OCoLC)1065945617 |z (OCoLC)1081241018 |z (OCoLC)1086939965 |z (OCoLC)1153495797 |z (OCoLC)1162051070 |z (OCoLC)1228550659 |z (OCoLC)1241931823 |z (OCoLC)1290040162 |z (OCoLC)1297159145 |z (OCoLC)1297621693 |z (OCoLC)1300548444 | ||
| 050 | 4 | |a QH431 |b .C55 2012eb | |
| 060 | 4 | |a 2013 J-068 | |
| 060 | 4 | |a QU 550 | |
| 072 | 7 | |a SCI |x 056000 |2 bisacsh | |
| 082 | 0 | 4 | |a 571.9/648 |2 23 |
| 049 | |a UAMI | ||
| 245 | 0 | 4 | |a The clinibook : |b clinical gene transfer : state of the art / |c edited by Odile Cohen-Haguenauer. |
| 260 | |a Paris : |b EDP Sciences, |c 2012. | ||
| 300 | |a 1 online resource (xxxviii, 545 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a data file |2 rda | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a pt. 1. Technologies and pre-clinical studies -- pt. 2. Clinical trials and regulatory issues. | |
| 546 | |a English. | ||
| 520 | |a This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Genetic transformation. | |
| 650 | 0 | |a Genetic vectors. | |
| 650 | 1 | 2 | |a Gene Transfer Techniques |
| 650 | 2 | 2 | |a Genetic Therapy |x methods |
| 650 | 2 | 2 | |a Genetic Therapy |x ethics |
| 650 | 2 | 2 | |a Genetic Vectors |
| 650 | 2 | 2 | |a Clinical Trials as Topic |
| 650 | 6 | |a Vecteurs de clonage. | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Anatomy & Physiology. |2 bisacsh | |
| 650 | 7 | |a Genetic vectors |2 fast | |
| 650 | 7 | |a Genetic transformation |2 fast | |
| 700 | 1 | |a Cohen-Haguenauer, Odile. | |
| 758 | |i has work: |a The clinibook (Text) |1 https://id.oclc.org/worldcat/entity/E39PCFM7drmTGMtY4F83QVm7d3 |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Cohen-Haguenauer, Odile. |t Clinibook : Clinical gene transfer state of the art. |d Les Ulis : EDP Sciences, ©2011 |z 9782842541712 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=3155343 |z Texto completo |
| 938 | |a De Gruyter |b DEGR |n 9782842542375 | ||
| 938 | |a EBL - Ebook Library |b EBLB |n EBL3155343 | ||
| 938 | |a ebrary |b EBRY |n ebr10667713 | ||
| 938 | |a EBSCOhost |b EBSC |n 555317 | ||
| 938 | |a YBP Library Services |b YANK |n 10306044 | ||
| 994 | |a 92 |b IZTAP | ||