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130309s2013 xx ob 001 0 eng d |
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|a 988493282
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|a 9781118355947
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|a 1118355946
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|q (hardback)
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|a RA1224.2 .E613 2012
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|a 615.3
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|a SCI013060
|2 bisacsh
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|a UAMI
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|a Matthiessen, Peter.
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|a Endocrine Disrupters :
|b Hazard Testing and Assessment Methods.
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|a Chicester :
|b Wiley,
|c 2013.
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|a 1 online resource (412 pages)
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|a text
|b txt
|2 rdacontent
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|a computer
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|a ENDOCRINE DISRUPTERS; CONTENTS; PREFACE; CONTRIBUTORS; CHAPTER 1 Ecotoxicity Test Methods for Endocrine-Disrupting Chemicals : AN INTRODUCTION; 1.1 BACKGROUND; 1.2 REGULATORY CONCERNS; 1.3 INVERTEBRATES; 1.4 VERTEBRATES; 1.5 TESTING SCHEMES FOR EDCs; REFERENCE; CHAPTER 2 Endocrine Disruption in Wildlife : BACKGROUND, EFFECTS, AND IMPLICATIONS; 2.1 BACKGROUND TO ENDOCRINE DISRUPTION; 2.1.1 Introduction; 2.1.2 Brief Account of the History of Endocrine Disruption; 2.1.3 What Are Endocrine-Disrupting Chemicals?; 2.1.4 Vertebrate Endocrine System; 2.1.5 Invertebrate Endocrine System.
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|a 2.1.6 Mechanisms of Endocrine Disruption2.1.7 Endocrine Disrupters in the Environment; 2.2 EFFECTS OF EDCs ON WILDLIFE; 2.2.1 Mammals; 2.2.2 Birds; 2.2.3 Reptiles and Amphibians; 2.2.4 Fish; 2.2.5 Invertebrates; 2.3 WEIGHT OF EVIDENCE AND ECOLOGICAL SIGNIFICANCE OF ED EFFECTS; 2.4 IMPLICATIONS FOR EFFECT ASSESSMENT AND TOXICITY TESTING; 2.5 NEED FOR MORE FIELD STUDIES AND AN INTEGRATED APPROACH; 2.6 CONCLUDING POINTS; REFERENCES; CHAPTER 3 The Regulatory Need for Tests to Detect EDCs and Assess Their Hazards to Wildlife.
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|a 3.1 EMERGING CONCERNS AND POLICY RESPONSES: FOCUSING ON EDCs AS A LARGE PSEUDO-UNIFORM GROUP OF SUBSTANCES3.1.1 Regulatory Action Among Public Concern, Policy, Stakeholder Interests, and Scientific Complexity: The Starting Point; 3.1.2 Policy Responses to the Initial General Concern: General Strategies; 3.2 GENERAL APPROACHES IN SUBSTANCE-RELATED REGULATORY FRAMEWORKS (EU); 3.2.1 Highlighted Role of ED Properties in General Parts of Regulatory Frameworks; 3.2.2 REACH: Authorization in Cases of "Very High Concern."
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|a 3.2.3 Plant Protection Products: Major Change from Directive 91/414 to New Regulation 1107/20093.2.4 Biocides; 3.2.5 Pharmaceuticals; 3.2.6 Other Regulatory Frameworks Not Primarily Related to Substances; 3.3 HOW TO MAKE EDC DEFINITIONS OPERATIONAL FOR SUBSTANCE-RELATED REGULATORY WORK; 3.4 FUTURE PERSPECTIVES; 3.5 CONCLUSIONS; REFERENCES; CHAPTER 4 Techniques for Measuring Endocrine Disruption in Insects; 4.1 INTRODUCTION; 4.1.1 Insects; 4.1.2 Insect Hormones; 4.1.3 Endocrine Disruption and Insects; 4.1.4 Development of Insecticides Targeting the Endocrine System; 4.2 METHODS.
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|a 4.2.1 Mechanistic Assays4.2.2 Apical Assays; 4.3 DISCUSSION; 4.3.1 Mechanism and Effect; 4.3.2 Exposure Considerations; 4.4 CONCLUSION; 4.5 ACKNOWLEDGMENTS; REFERENCES; CHAPTER 5 Crustaceans; 5.1 INTRODUCTION; 5.2 BACKGROUND TO CRUSTACEAN ENDOCRINOLOGY; 5.2.1 General; 5.2.2 Overview of the Crustacean Endocrine System; 5.3 STATE OF THE ART: WHAT DO WE KNOW ABOUT ENDOCRINE DISRUPTION IN CRUSTACEANS?; 5.3.1 General; 5.3.2 Daphnia sp.; 5.3.3 Barnacles; 5.3.4 Copepods; 5.3.5 Amphipods; 5.3.6 Mysids; 5.3.7 Other Studies Using Larger Crustaceans.
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|a 5.4 available subchronic/chronic standard test protocols.
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|a Enables researchers to assess the effects of endocrine disrupters as well as comply with new environmental regulations Endocrine disrupters are chemicals-both man-made and natural-that interfere with the body's endocrine system, potentially resulting in adverse developmental, reproductive, neurological, and immune effects. In recent years, a number of regulatory authorities around the world have drafted or enacted legislation that requires the detection and assessment of the effects of endocrine disrupters on both humans and wildlife. In response, this book provides comprehensi.
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|a Print version record.
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|a Includes bibliographical references and index.
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Endocrine disrupting chemicals
|x Toxicity testing.
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650 |
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|a Endocrine disrupting chemicals
|x Environmental aspects.
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650 |
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|a Endocrine toxicology.
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|a Perturbateurs endocriniens
|x Toxicité.
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|a Perturbateurs endocriniens
|x Aspect de l'environnement.
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|a Toxicologie endocrinienne.
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|a SCIENCE
|x Chemistry
|x Industrial & Technical.
|2 bisacsh
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|a Endocrine toxicology
|2 fast
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|i has work:
|a Endocrine disrupters: hazard testing and assessment methods (Text)
|1 https://id.oclc.org/worldcat/entity/E39PD3PgmHdH9Fj7j44JvYDwRX
|4 https://id.oclc.org/worldcat/ontology/hasWork
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776 |
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|i Print version:
|a Matthiessen, Peter.
|t Endocrine Disrupters : Hazard Testing and Assessment Methods.
|d Chicester : Wiley, ©2013
|z 9780470932094
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