Protein-protein interactions in drug discovery /

Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the book describes examples of prote...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Dömling, Alexander
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Weinheim : Wiley-VCH, 2013.
Colección:Methods and principles in medicinal chemistry ; v. 56.
Temas:
Protein-protein interactions.
Protein binding.
Proteins > Inhibitors.
Carrier proteins.
Carrier Proteins
Drug Discovery
Protein Interaction Domains and Motifs
Protein Binding
Interactions protéine-protéine.
Protéines > Fixation.
Protéines > Inhibiteurs.
Protéines de liaison.
MEDICAL > Drug Guides.
MEDICAL > Nursing > Pharmacology.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
Carrier proteins
Protein binding
Protein-protein interactions
Acceso en línea:Texto completo
Descripción
Sumario:Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the book describes examples of protein targets for which small molecule modulators have been developed, covering such diverse fields as cancer, autoimmune disorders and infectious diseases. Tailor-made for the practicing medicinal chemist, this ready reference includes a wide selection of case studies taken straight from the devel.
Descripción Física:1 online resource (xxi, 314 pages) : illustrations
Bibliografía:Includes bibliographical references and index.
ISBN:9783527648238
3527648232
9783527648207
3527648208

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