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Antibiotics and Antibiotic Resistance.

This book, which is the translated version of a Swedish book, combines a general introduction of a variety of antibiotics with a more in-depth discussion of resistance. The focus on resistance in learning about antibiotics will help future scientists recognize the problem antibiotics resistance pose...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Sköld, Ola
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Chicester : Wiley, 2011.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • ANTIBIOTICS AND ANTIBIOTIC RESISTANCE; CONTENTS; Preface; 1 ANTIBIOTICS: THE GREATEST TRIUMPH OF SCIENTIFIC MEDICINE; Selectivity; Development of Resistance; Sulfonamide: The First Antibacterial Agent Acting Selectively; Chemotherapeutics and Antibiotics; Penicillin: The First Antibiotic; The First Therapeutic Trial; Rediscovery of Penicillin by a Basic Scientific Approach; Betalactams; Streptomycin: The Second Antibiotic in the History of Antibacterial Agents; The First Remedy for Tuberculosis; Conclusion; 2 DISTRIBUTION OF ANTIBIOTICS; Quantitative Evaluation of Antibiotics Consumption.
  • Defined Daily DosesInternational Distribution of Antibiotics: A Scandinavian Example; Control of Antibiotics Overuse; 3 SULFONAMIDES AND TRIMETHOPRIM; General Aspects Regarding the Development of Resistance; Sulfonamides; Sulfonamides as Remedies; Resistance to Sulfonamide; Resistance to Sulfonamides in Neisseria meningitidis; Characterization of the Sulfonamide-Resistant Dihydropteroate Synthase in N. meningitidis; Characterization of the Other Sulfonamide-Resistant Dihydropteroate Synthase in N. meningitidis; Resistance to Sulfonamides in Streptococcus pyogenes.
  • Resistance to Sulfonamides in Campylobacter jejuniResistance to Sulfonamides in Streptococcus pneumoniae; Resistance to Sulfonamides in Pneumocystis jiroveci (carinii); Resistance to Sulfonamides in Staphylococcus aureus and S. haemolyticus; Resistance to Sulfonamides in Mycobacterium leprae; Plasmid-Borne Resistance to Sulfonamides; Trimethoprim; Innate Resistance to Trimethoprim; Chromosomal Resistance to Trimethoprim; Plasmid-Borne Resistance to Trimethoprim; Possible Pathogenicity Change in C. jejuni by Acquiring Trimethoprim Resistance Genes.
  • Experimental Test of the Reversibility of Trimethoprim ResistanceConclusion; 4 PENICILLINS AND OTHER BETALACTAMS; The Betalactam Ring: The Characteristic of all Betalactams; The Antibacterial Mechanism of Betalactams; Penicillins; Penicillins with an Enlarged Spectrum; Penicillins Stable to Penicillinases; Counteracting Resistance by the Inhibition of Betalactamases; Other Antibacterial Betalactams; Cephalosporins; Monobactams; Thienamycins; Betalactamases; Horizontal Spread of Betalactamases; Penicillin-Binding Proteins; Resistance to Betalactams by Changes in the PBPs.
  • A Very Old Prophecy Came True5 GLYCOPEPTIDES; Mechanism of Antibacterial Action; Resistance; Avoparcin and Clinical Resistance to Glycopeptides; Vancomycin as an Antibiotic of Last Resort; 6 AMINOGLYCOSIDES; The Antibacterial Mechanism of Streptomycin; Bactericidal Effect; Clinical Side Effects; Bacterial Resistance to Aminoglycosides; Horizontal Spread of Aminoglycoside Resistance; Conclusion; 7 OTHER ANTIBIOTICS INTERFERING WITH BACTERIAL PROTEIN SYNTHESIS; Chloramphenicol; Clinical Side Effects; Bacterial Resistance to Chloramphenicol; Tetracyclines; Mechanism of Action.