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Treatment-Resistant Depression.

The first book devoted to a challenging disorder that affects millions of people around the world. Essential reading for all psychiatrists who manage these patients.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Kasper, S. (Siegfried)
Otros Autores: Montgomery, Stuart A.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Wiley, 2013.
Edición:2nd ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Treatment-resistant Depression; Copyright; Contents; List of Contributors; Foreword; Chapter 1 Definitions and Predictors of Treatment resistant Depression; Summary; Introduction; Definition of TRD: historical perspective; TRD staging models; Thase and Rush model (1997); European staging model (1999); Massachusetts general hospital staging model (2003); Maudsley staging model (2009); Definition of TRD in clinical trials; Clinical characteristics and predictors of TRD; Conclusions; References; Chapter 2 Treatment-resistant Depression: A Separate Disorder
  • A New Approach; Summary; Introduction.
  • Historical backgroundCurrent TRD concepts and their limitations; Towards a new definition and nosology; Towards a new terminology: malignant, pernicious or virulent depression; References; Chapter 3 Genetics of Treatment-resistant Depression; Summary; Introduction; Genetic polymorphisms and antidepressant efficacy; Antidepressant pharmacodynamics; Antidepressant pharmacokinetics; Conclusions; References; Chapter 4 Is There a Role for Switching Antidepressants in Treatment-resistant Depression?; Summary; Introduction; Raising the dose; Switching antidepressant pharmacological class.
  • Serotonin norepinephrine reuptake inhibitorsSelective serotonin reuptake inhibitors; Guidelines on second-step treatment of nonresponders; Does switching class of antidepressant improve response?; Conclusions; References; Chapter 5 The Role of Atypical Antipsychotics in Inadequate-response and Treatment-resistant Depression; Summary; Introduction; Epidemiology: prescription data; Efficacy of SGAs in TRD; Side effects; Conclusions; References; Chapter 6 Lithium, Thyroid Hormones and Further Augmentation Strategies in Treatment-resistant Depression; Summary; Introduction; Augmentation studies.
  • LithiumThyroid hormones; Anticonvulsants; Dopamine agonists; Psychostimulants; Buspirone; S-Adenosyl methionine; Omega-3 polyunsaturated fatty acids; Combined treatment with antidepressants from the beginning: acceleration studies; Lithium; Triiodothyronine; Pindolol; Polyunsaturated fatty acids; Conclusions; References; Chapter 7 The Role of Nonpharmacological Interventions in Treatment-resistant Depression; Summary; Introduction; Electroconvulsive therapy; Indications, contraindications and risks; Mechanism of action; Procedure and stimulation parameters; Side effects; Outlook.
  • Repetitive transcranial magnetic stimulationIndications, contraindications and risk; Mechanism of action; Procedure and stimulation parameters; Side effects; Outlook; Vagus nerve stimulation; Indications, contraindications and risk; Mechanism of action; Procedure and stimulation parameters; Side effects; Outlook; Deep-brain stimulation; Indications, contraindications and risk; Mechanism of action and targets; Procedure and stimulation parameters; Side effects; Outlook; Ethical considerations; Magnetic seizure therapy; Indications, contraindications and risk; Mechanism of action.