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Analogue-based drug discovery III /

"Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the succe...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Fischer, János (Editor ), Ganellin, C. R. (C. Robin) (Editor ), Rotella, David P. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Weinheim : Wiley-VCH, [2013]
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Analogue-based drug discovery III /  |c edited by János Fischer, C. Robin Ganellin, David P. Rotella. 
246 3 |a Analogue-based drug discovery 3 
246 3 |a Analog-based drug discovery III 
264 1 |a Weinheim :  |b Wiley-VCH,  |c [2013] 
264 4 |c ©2013 
300 |a 1 online resource (xviii, 385 pages) :  |b illustrations, portraits 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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588 0 |a Online resource; title page from PDF title page (viewed June 30, 2014). 
505 0 0 |t General Aspects. Pioneer and Analogue Drugs /  |r Janos Fischer, C Robin Ganellin, David P Rotella --  |t Competition in the Pharmaceutical Drug Development /  |r Christian Tyrchan, Fabrizio Giordanetto --  |t Metabolic Stability and Analogue-Based Drug Discovery /  |r Amit S Kalgutkar, Antonia F Stepan --  |t Use of Macrocycles in Drug Design Exemplified with Ulimorelin, a Potential Ghrelin Agonist for Gastrointestinal Motility Disorders /  |r Mark L Peterson, Hamid Hoveyda, Graeme Fraser, Eric Marsault, Rene Gagnon --  |t Drug Classes. The Discovery of Anticancer Drugs Targeting Epigenetic Enzymes /  |r A Ganesan --  |t Thienopyridyl and Direct-Acting P2Y Receptor Antagonist Antiplatelet Drugs /  |r Joseph A Jakubowski, Atsuhiro Sugidachi --  |t Selective Estrogen Receptor Modulators /  |r Amarjit Luniwal, Rachael Jetson, Paul Erhardt --  |t Discovery of Nonpeptide Vasopressin V2 Receptor Antagonists /  |r Kazumi Kondo, Hidenori Ogawa --  |t The Development of Cysteinyl Leukotriene Receptor Antagonists /  |r Peter R Bernstein --  |t Case Studies. The Discovery of Dabigatran Etexilate /  |r Norbert Hauel, Andreas Clemens, Herbert Nar, Henning Priepke, Joanne van Ryn, Wolfgang Wienen --  |t The Discovery of Citalopram and Its Refinement to Escitalopram /  |r Klaus P Bogeso, Connie Sanchez --  |t Tapentadol : From Morphine and Tramadol to the Discovery of Tapentadol /  |r Helmut Buschmann --  |t Novel Taxanes: Cabazitaxel Case Study /  |r Herve Bouchard, Dorothee Semiond, Marie-Laure Risse, Patricia Vrignaud --  |t Discovery of Boceprevir and Narlaprevir: A Case Study for Role of Structure-Based Drug Design /  |r Srikanth Venkatraman, Andrew Prongay, George F Njoroge --  |t A New-Generation Uric Acid Production Inhibitor: Febuxostat /  |r Ken Okamoto, Shiro Kondo, Takeshi Nishino. 
504 |a Includes bibliographical references and index. 
520 |a "Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs. The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtually every researcher in drug discovery and pharmaceutical chemistry, and--together with the previous volumes--constitutes the first systematic approach to drug analogue development"--Publisher's website. 
546 |a English. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Drug development. 
650 0 |a Drugs  |x Design. 
650 1 2 |a Pharmaceutical Preparations  |x chemical synthesis 
650 2 2 |a Drug Design 
650 2 2 |a Models, Molecular 
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650 7 |a Drug development  |2 fast 
655 4 |a Internet Resources. 
655 4 |a Portraits. 
700 1 |a Fischer, János,  |e editor. 
700 1 |a Ganellin, C. R.  |q (C. Robin),  |e editor. 
700 1 |a Rotella, David P.,  |e editor. 
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