Cargando…
Purine and Pyrimidine Metabolism.
| Clasificación: | Libro Electrónico |
|---|---|
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Wiley
2009.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Purine and Pyrimidine Metabolism; Contents; Chairman's opening remarks; Purine and pyrimidine metabolism : pathways, pitfalls and perturbations; Discussion; Microbial models and regulatory elements in the control of purine metabolism; Discussion; Molecular nature of enzyme regulation in purine biosynthesis; Discussion; Genetic heterogeneity at the locus for hypoxanthine-guanine phosphoribosyltransferase; Discussion; Factors in the pathogenesis of the brain damage and anaemia in the Lesch-Nyhan syndrome; Discussion
- Hypoxanthine-guanine phosphoribosyltransferase activity in individual erythrocytes: autoradiographic studies in heterozygotDiscussion; Purine biosynthesis in mutant mammalian cells; Discussion; Purine and pyrimidine nucleotides in some mutant human lymphoblasts; Discussion; Superactivity of phosphoribosylpyrophosphate synthetase, due to feedback resistance, causing purine overproduction and gout; Discussion; Dietary feedback regulation of purine and pyrimidine biosynthesis in man; Discussion; Implications of disorders of purine metabolism for the kidney and the urinary tract; Discussion
- The role of de novo purine synthesis in lymphocyte transformationDiscussion; Purine metabolism and control of cell proliferation; Discussion; The effect of adenosine on lymphoid cell proliferation and antibody formation; Discussion; Characterization of human adenosine deaminase; Discussion; The purinergic nerve hypothesis; Discussion; Inherited metabolic disease: prospects for the future in both basic and clinical research; Discussion; General discussion; Purine as regulators; Extracellular effects of adenosine; Membrane transport; Pyrimidine metabolism and immune function
- Allopurinol and purine transportModel systems for the study of purine and pyrimidine metabolism and their limitations; Animal models; Assessment of treatment : the Lesch-Nyhan syndrome; Ribose 5-phosphate and the oxidative pentose shunt in the regulation of purine synthesis de novo; Index of contributors; Subject index