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Growth Factors in Biology and Medicine.
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken :
John Wiley & Sons,
2009.
|
| Colección: | Novartis Foundation Symposia.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Growth factors in biology and medicine; Contents; Introduction; Growth factors in mammalian embryogen-esis; Discussion; The EGF receptor kinase: evidence for allos- teric activation and intramolecular self-phosphorylation; Discussion; Role of growth factors in oncogenesis: growth factor-proto-oncogene pathways of mitogenesis; Discussion; Signalling mitogene- sis in 3T3 cells: role of Ca*+-sensitive, phospholipid-dependent protein kinase; Discussion; The PDGF-inducible 'compe- tence genes': intracellular mediators of the mitogenic response; Discussion.
- Platelet-derived growth factor: its potential roles in wound-healing, atherosclerosis, neoplasia, and growth and developmentDiscussion; Nerve growth factor; Discussion; The role of haemopoietic cell growth factor (interleukin 3) in the development of haemopoietic cells; Discussion; Haemopoietic growth factors: structure and receptor interac- tions; Discussion; In vivo effects of the insulin-like growth factors (IGFs) in the hypophysectomized rat: comparison with human growth hormone and the possible role of the specific IGF carrier proteins; Discussion.
- Protein phosphorylation and growth controlDiscussion; Receptors for the phorbol ester tumour promoters; Discussion; Ectopic peptides released by a human mela- noma cell line that modulate the transformed phenotype; Discussion; A growth regula- tory factor that can both inhibit and stimulate growth; Discussion; Final general discussion Receptor modulation and signalling systems; Biological functions of growth factors; Medical aspects of growth factors; Index of contributors; Subject index.