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Monoamine Oxidase and its Inhibition.
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken :
John Wiley & Sons,
2009.
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| Colección: | Novartis Foundation Symposia.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Monoamine Oxidase and its Inhibition; Contents; Introduction; The nature and locations of the multiple forms of monoamine oxidase; Discussion; The action of acetylenic inhibitors on mitochondrial monoamine oxidase : structure of the flavin site in the inhibited enzyme; Cysteinyl flavin in monoamine oxidase from the central nervous system; Discussion of the two preceding papers; Monoamine oxidase inhibitors and the transformation of monoamine oxidases; Discussion; Nutritional requirements for amine metabolism in vivo; Discussion; Physiological aspects of the oxidative deamination of monoamines.
- DiscussionAnalysis of the pharmacological effects of selective monoamine oxidase inhibitors; Discussion; The use of selective monoamine oxidase inhibitor drugs for evaluating pharmacological and physiological mechanisms; Discussion; The part played by monoamine oxidase in the inactivation of catecholamines in intact tissues; Discussion; Can the intra- and extra-homoneuronal metabolism of catecholamines be distinguished in the mammalian central nervous system; Discussion; Use of a behavioural model to study the action of monoamine oxidase inhibition in vivo; Discussion.
- Relations between the degree of monoamine oxidase inhibition and some psychopharmacological respon- ses to monoamine oxidase inhibitors in ratsDiscussion; Introduction to clinical aspects of monoamine oxidase inhibitors in the treatment of depression; Discussion; The relationship between classification and response to drugs in affective disorders- problems posed by drug response in af; Discussion; Variations in monoamine oxidase activity in some human disease states; Discussion; Clinical, genetic, hormonal and drug influences on the activity of human platelet monoamine oxidase.
- An investigation of platelet monoamine oxidase activity in schizophrenia and schizo-affective psychosisDiscussion of the two preceding papers; General discussion; Future investigations; Standardization of assays; Conclusion; Appendix 1 : Assay of monoamine oxidase; Appendix 2: Preparation of human platelets; Index of contributors; Subject index.