The quest for cortisone /

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"In 1948, when "Mrs. G.," hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound -- cortisone -- her physicians were awestruck by her transformation from enervated to energized. After eighteen years of biochemical research, th...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Rooke, Thom W.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: East Lansing [Mich.] : Michigan State University Press, ©2012.
Temas:
Kendall, Edward C. > (Edward Calvin), > 1886-1972.
Hench, Philip S. > (Philip Showalter), > 1896-1965.
Hench, Philip S > (Philip Showalter), > 1896-1965.
Kendall, Edward C > (Edward Calvin), > 1886-1972.
Hench, Philip S. > (Philip Showalter), > 1896-1965
Kendall, Edward C. > (Edward Calvin), > 1886-1972
Mayo Clinic.
Mayo Clinic
Cortisone > History.
Drug development.
Cortisone > history
Clinical Trials as Topic > history
Cortisone > therapeutic use
Drug Discovery > history
Drug Evaluation > history
History, 20th Century
Cortisone > Histoire.
Médicaments > Développement.
Médecine > Histoire > 20e siècle.
MEDICAL > History.
Cortisone
Drug development
United States
History
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Introduction
  • Addison and his disease
  • Introducing Dr. Kendall
  • Life after the thyroid
  • Introducing Dr. Hench
  • Nice guys, saints, eccentrics, and geniuses
  • 1929 and the decision to hunt for cortisone
  • Another Kendall false start, another great announcement
  • Kendall strikes out again
  • Kendall presses on
  • Score: Szent-Györgyi-1; Kendall-0
  • Transitions and travels
  • War looms
  • Hench meets Kendall
  • World War II and military steroid research
  • Plants, politicians, and more pessimism
  • Good-bye Marker, hello Sarett
  • Hench returns to Mayo
  • Push on? Give up?
  • The decision to test compound E on rheumatoid arthritis
  • The amazing Mrs. G.
  • A promising start
  • The bad and the ugly
  • Progress and setbacks
  • Convincing the skeptics
  • Announcement
  • The prize
  • Stockholm
  • Aftermath
  • Twilight
  • The end of the show
  • Notes.

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