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Translational neuroscience : applications in psychiatry, neurology, and neurodevelopmental disorders /
A comprehensive analysis of translational neuroscience, covering all major areas of psychiatry, neurology and neurodevelopmental disorders.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge :
Cambridge University Press,
2012.
|
| Colección: | Cambridge medicine (Series)
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Translational neuroscience : |b applications in psychiatry, neurology, and neurodevelopmental disorders / |c edited by James E. Barrett, Joseph T. Coyle, Michael Williams. |
| 260 | |a Cambridge : |b Cambridge University Press, |c 2012. | ||
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
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| 490 | 1 | |a Cambridge medicine | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |6 880-01 |a The discovery and development of drugs to treat psychiatric disorders : historical perspective / Michael Williams and James E. Barrett -- Translational approaches to the treatment of anxiety disorders / Charles F. Gillespie, Tamara Weiss, and Kerry J. Ressler -- Mood disorders / Jorge A. Quiroz [and others] -- Schizophrenia / Donald C. Goff and Darrick T. Balu -- Addictive disorders / Charles P. O'Brien -- Section summary and perspectives : translational medicine in psychiatry / Joseph T. Coyle -- Historical perspectives on the discovery and development of drugs to treat neurological disorders / Michael Williams and Joseph T. Coyle -- Alzheimer's disease / Donald L. Price [and others] -- Pain therapeutics / Anthony W. Bannon -- Multiple sclerosis / Alfred W. Sandrock Jr. and Richard A. Rudick -- Parkinson's disease / Jiang-Fan Chen -- Amyotrophic lateral sclerosis / Nicholas J. Maragakis -- Epilepsy / Maciej Gasior and Frank Wiegand -- Section summary and perspectives : translational medicine in neurology / James E. Barrett and Joseph T. Coyle -- Historical perspectives on the use of therapeutic agents to treat neurodevelopmental disorders / Kimberly A. Stigler [and others] -- Autism spectrum disorders / Timothy P.L. Roberts [and others] -- Attention deficit hyperactivity disorder / Craig W. Berridge, David M. Devilbiss, and Amy F.T. Arnsten -- Epigenetic mechanisms in central nervous system disorders / Swati Gupta, Ryley Parrish, and Farah D. Lubin -- Section summary and perspectives : neurodevelopmental disorders and regulation of epigenetic changes / James E. Barrett and Joseph T. Coyle -- Promises and challenges of translational research in neuropsychiatry / David L. Braff. | |
| 520 | |a A comprehensive analysis of translational neuroscience, covering all major areas of psychiatry, neurology and neurodevelopmental disorders. | ||
| 588 | 0 | |a Print version record. | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Nervous system |x Diseases. | |
| 650 | 0 | |a Drug development. | |
| 650 | 0 | |a Neurosciences. | |
| 650 | 0 | |a Mental illness. | |
| 650 | 1 | 2 | |a Nervous System Diseases |
| 650 | 2 | 2 | |a Drug Discovery |
| 650 | 2 | 2 | |a Mental Disorders |
| 650 | 2 | 2 | |a Neurosciences |x methods |
| 650 | 2 | 2 | |a Translational Research, Biomedical |x methods. |
| 650 | 2 | |a Neurosciences | |
| 650 | 4 | |a Nervous system |x Diseases. | |
| 650 | 4 | |a Neurosciences |x Research |x Methodology. | |
| 650 | 6 | |a Système nerveux |x Maladies. | |
| 650 | 6 | |a Médicaments |x Développement. | |
| 650 | 6 | |a Neurosciences. | |
| 650 | 6 | |a Maladies mentales. | |
| 650 | 7 | |a mental disorders. |2 aat | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Nervous System (incl. Brain) |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Neurology. |2 bisacsh | |
| 650 | 7 | |a Drug development |2 fast | |
| 650 | 7 | |a Mental illness |2 fast | |
| 650 | 7 | |a Nervous system |x Diseases |2 fast | |
| 650 | 7 | |a Neurosciences |2 fast | |
| 700 | 1 | |a Barrett, James E. |q (James Elmer), |d 1934- |1 https://id.oclc.org/worldcat/entity/E39PCjwJmYDRTtXCDBtRpHHqHC | |
| 700 | 1 | |a Coyle, Joseph T. | |
| 700 | 1 | |a Williams, Michael, |d 1947 January 3- |1 https://id.oclc.org/worldcat/entity/E39PCjDfFfp6986mgMyK37KfMP | |
| 758 | |i has work: |a Translational neuroscience (Text) |1 https://id.oclc.org/worldcat/entity/E39PCG8Drq47jPHkbf6WWqTdV3 |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Barrett, James E. |t Translational Neuroscience. |d Cambridge : Cambridge University Press, 2012 |z 9780521519762 |w (DLC) 2011043658 |w (OCoLC)758244387 |
| 830 | 0 | |a Cambridge medicine (Series) | |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=944697 |z Texto completo |
| 880 | 8 | |6 505-01/(S |a Current treatments -- Hurdles to new therapeutics -- Biomarkers -- Genetics of neurodegenerative diseases -- Genetic factors -- Alzheimer's disease -- the a myloid and tau hypotheses -- Alzheimer's disease and anti-inflammatory drugs -- Alzheimer's disease and metabolic syndrome -- New approaches to treat Parkinson's disease -- Clinical score card for neurodegenerative diseases -- Common themes in neurodegenerative disease drug discovery -- Gene-based drug discovery in neurodegenerative diseases -- Future translational aspects -- Acknowledgments -- References -- Chapter 8: Alzheimer's disease -- Clinical and laboratory features of individuals with MCI and AD -- Clinical features, neuropathology, and biochemistry -- Current treatment -- Amyloidogenesis, APP, and amyloid precursor-like proteins (APLPs) -- BACE1 and BACE2 -- γ-Secretase -- α-Secretase -- Genetics -- FAD and influences of risk factors -- Other risk genes -- Transgenic models of Aβ amyloidosis and tauopathies -- Experimental manipulations and potential therapeutic strategies -- Conclusions -- Acknowledgments -- References -- Chapter 9: Pain therapeutics -- Overview of pain states -- Current pharmacological approaches to pain management -- Nociceptive pain -- Inflammatory pain -- Neuropathic pain -- Research and development in pain therapeutics -- Animal models of pain -- Acute or nociceptive pain models -- Inflammatory pain models -- Neuropathic pain models -- Cancer pain -- Animal models of pain: are they translational models-- Use of translational medicine for the discovery of novel treatments of pain -- Experimental pain models in humans -- Neuroimaging -- Conclusions -- References -- Chapter 10: Multiple sclerosis -- A historical perspective on the evolution of disease-modifying treatments -- Pathogenesis -- Factors that improve the efficiency of translational medicine. | |
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