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Vaccinology : Principles and Practice.
Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requir...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken :
John Wiley & Sons,
2012.
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| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe. Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human applicationIncludes evaluation of vaccine efficacy and safetyDetails clinical trial design, including regulatory requirements. |
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| Notas: | Antibody maintenance is dependent on the age of the host. |
| Descripción Física: | 1 online resource (554 pages) |
| Bibliografía: | ReferencesCHAPTER 6 Immunologic Memory: B Cells; Introduction; Human evaluation of B-cell vaccine responses; Variability in antibody maintenance is dependent on the type of vaccine; Primary B-cell immune response; Secondary B-cell immune responses; Factors important for long-lived plasma cell generation; Heterogeneity of the circulating newly formed ASCs; Models of long-lived plasma cells maintenance; Heterogeneity of human memory B-cell subsets; Current schemes of classification of human memory B-cell populations; Measuring memory B-cell responses to vaccines. |
| ISBN: | 9781118345337 1118345339 |