Systems Biology : Applications in Cancer-Related Research /
This volume presents an overview of recent developments in systems biology and their applications in cancer-related research. The ongoing advances in our understanding of genomics and proteomics, coupled with the development of new and more robust tools, have led to an emphasis on analyzing biologic...
Clasificación: | Libro Electrónico |
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Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Singapore :
World Scientific,
2012.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- pt. I. Gene/protein networks and pathways. 1. Introduction to systems biology / Hsueh-Fen Juan. 2. Gene network construction for molecular regulation / Hsueh-Fen Juan and Hsuan-Cheng Huang. 3. MicroRNA regulation in cellular networks / Hsueh-Fen Juan and Hsuan-Cheng Huang. 4. Disease modules in protein-protein interaction networks / Hsueh-Fen Juan and Hsuan-Cheng Huang. 5. Biomolecular pathway modeling / Feng-Sheng Wang and Wu-Hsiung Wu
- pt. II. High-throughput omics data and analysis. 6. ChIP-seq analytics: methods and systems to improve ChIP-seq peak identification / Stuart Brown [and others]. 7. Discovery of transcription factor binding sites and its applications in cancer study / Chien-Yu Chen. 8. Cancer epigenomics / Jer-Wei Chang and Yi-Ching Wang. 9. Cancer phosphoproteomics: tools and emerging applications for mining the phosphoproteome in cancer biology / Hsin-Yi Wu [and others]. 10. Predicting microRNAs / Arthur Chun-Chieh Shih and Tsunglin Liu. 11. MicroRNA research in cancer biology: databases and tools / Hsien-Da Huang
- pt. III. Applications for biomarkers and drug discovery. 12. The application of the next-generation sequencing technologies in cancer research / Lihua Cheng, Hong Xu and Biaoyang Lin. 13. Membrane proteomics for the opportunity of cancer biomarker and drug target discovery / Chia-Li Han [and others]. 14. Structure-based systems biology and drug design in cancer research / Chun-Hua Hsu. 15. Discovering drug targets for cancer therapy / Tsui-Chin Huang, Hsin-Yi Chang and Hsueh-Fen Juan.