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Systems Biology : Applications in Cancer-Related Research /

This volume presents an overview of recent developments in systems biology and their applications in cancer-related research. The ongoing advances in our understanding of genomics and proteomics, coupled with the development of new and more robust tools, have led to an emphasis on analyzing biologic...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Juan, Hsueh-Fen, Huang, Hsuan-Cheng
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore : World Scientific, 2012.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • pt. I. Gene/protein networks and pathways. 1. Introduction to systems biology / Hsueh-Fen Juan. 2. Gene network construction for molecular regulation / Hsueh-Fen Juan and Hsuan-Cheng Huang. 3. MicroRNA regulation in cellular networks / Hsueh-Fen Juan and Hsuan-Cheng Huang. 4. Disease modules in protein-protein interaction networks / Hsueh-Fen Juan and Hsuan-Cheng Huang. 5. Biomolecular pathway modeling / Feng-Sheng Wang and Wu-Hsiung Wu
  • pt. II. High-throughput omics data and analysis. 6. ChIP-seq analytics: methods and systems to improve ChIP-seq peak identification / Stuart Brown [and others]. 7. Discovery of transcription factor binding sites and its applications in cancer study / Chien-Yu Chen. 8. Cancer epigenomics / Jer-Wei Chang and Yi-Ching Wang. 9. Cancer phosphoproteomics: tools and emerging applications for mining the phosphoproteome in cancer biology / Hsin-Yi Wu [and others]. 10. Predicting microRNAs / Arthur Chun-Chieh Shih and Tsunglin Liu. 11. MicroRNA research in cancer biology: databases and tools / Hsien-Da Huang
  • pt. III. Applications for biomarkers and drug discovery. 12. The application of the next-generation sequencing technologies in cancer research / Lihua Cheng, Hong Xu and Biaoyang Lin. 13. Membrane proteomics for the opportunity of cancer biomarker and drug target discovery / Chia-Li Han [and others]. 14. Structure-based systems biology and drug design in cancer research / Chun-Hua Hsu. 15. Discovering drug targets for cancer therapy / Tsui-Chin Huang, Hsin-Yi Chang and Hsueh-Fen Juan.