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Protein-ligand interactions /
Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interaction, followed by a comparison of the four key expe...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Weinheim :
Wiley-VCH,
©2012.
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| Colección: | Methods and principles in medicinal chemistry ;
v. 53. |
| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interaction, followed by a comparison of the four key experimental methods (calorimetry, surface plasmon resonance, NMR and X-ray crystallography) used in generating interaction data. The second half of the book is devoted to in-silico methods of modeling and predicting molecular recognition and binding. Here, as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at unresolved challenges, and the strategies to address them. |
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| Descripción Física: | 1 online resource (xx, 339 pages) : illustrations |
| Bibliografía: | Includes bibliographical references and index. |
| ISBN: | 9783527645978 3527645977 9783527645947 3527645942 9786613639820 6613639826 |