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Toward precision medicine : building a knowledge network for biomedical research and a new taxonomy of disease /

"Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward precision medicine explores the feasibility and need for "a ne...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores Corporativos: National Research Council (U.S.). Committee on A Framework for Developing a New Taxonomy of Disease, National Research Council (U.S.). Board on Life Sciences
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington, D.C. : National Academies Press, 2011.
Colección:Online access: National Academy of Sciences National Academies Press.
Online access: NCBI NCBI Bookshelf.
Temas:
Acceso en línea:Texto completo

MARC

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049 |a UAMI 
110 2 |a National Research Council (U.S.).  |b Committee on A Framework for Developing a New Taxonomy of Disease. 
245 1 0 |a Toward precision medicine :  |b building a knowledge network for biomedical research and a new taxonomy of disease /  |c Committee on a framework for developing a new taxonomy of disease ; Board on Life Sciences ; Division on Earth and Life Studies. 
264 1 |a Washington, D.C. :  |b National Academies Press,  |c 2011. 
300 |a 1 online resource (xiii, 128 pages) :  |b color illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a data file  |2 rda 
504 |a Includes bibliographical references. 
505 0 |a Introduction -- Why now? -- What would a knowledge network and new taxonomy look like? -- How do we get there? 
520 |a "Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward precision medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward precision medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy."--Publisher's description. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a APACHE (Disease classification system) 
650 0 |a Medicine  |x Research. 
650 0 |a Immunotaxonomy. 
650 0 |a Precision medicine. 
650 1 2 |a APACHE 
650 1 2 |a Disease  |x classification 
650 1 2 |a Information Dissemination 
650 2 2 |a Information Storage and Retrieval  |x methods 
650 2 2 |a Information Management  |x organization & administration 
650 2 2 |a Precision Medicine 
650 2 2 |a Terminology as Topic 
650 6 |a APACHE (Système d'évaluation) 
650 6 |a Médecine  |x Recherche. 
650 6 |a Médecine de précision. 
650 7 |a HEALTH & FITNESS  |x Holism.  |2 bisacsh 
650 7 |a HEALTH & FITNESS  |x Reference.  |2 bisacsh 
650 7 |a MEDICAL  |x Alternative Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Atlases.  |2 bisacsh 
650 7 |a MEDICAL  |x Essays.  |2 bisacsh 
650 7 |a MEDICAL  |x Family & General Practice.  |2 bisacsh 
650 7 |a MEDICAL  |x Holistic Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Osteopathy.  |2 bisacsh 
650 7 |a Precision medicine  |2 fast 
650 7 |a APACHE (Disease classification system)  |2 fast 
650 7 |a Immunotaxonomy  |2 fast 
650 7 |a Medicine  |x Research  |2 fast 
710 2 |a National Research Council (U.S.).  |b Board on Life Sciences. 
758 |i has work:  |a Toward Precision Medicine (Text)  |1 https://id.oclc.org/worldcat/entity/E39PD3PKXqctdjD7FbWTGQyY8C  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |a Committee on a framework for developing a new taxonomy of disease.  |t Toward precision medicine.  |d Washington, D.C. : National Academies Press, 2011  |w (DLC) 2011943146 
830 0 |a Online access: National Academy of Sciences National Academies Press. 
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