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Therapeutic Proteins : Strategies to Modulate Their Plasma Half-life.
For this ready reference, the internationally renowned authority in the field, Roland Kontermann, has assembled a team of outstanding contributors from industry and academia to convey the worldwide knowledge on modifying therapeutic proteins in order to optimize their pharmacological potential. The...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Weinheim :
John Wiley & Sons,
2011.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Kontermann, Roland. | |
| 245 | 1 | 0 | |a Therapeutic Proteins : |b Strategies to Modulate Their Plasma Half-life. |
| 260 | |a Weinheim : |b John Wiley & Sons, |c 2011. | ||
| 300 | |a 1 online resource (374 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 520 | |a For this ready reference, the internationally renowned authority in the field, Roland Kontermann, has assembled a team of outstanding contributors from industry and academia to convey the worldwide knowledge on modifying therapeutic proteins in order to optimize their pharmacological potential. The result is a comprehensive work covering all approaches and aspects of the topic in one handy volume, making this indispensable reading for companies and research institutions working on the development of biopharmaceuticals. | ||
| 505 | 0 | |a Therapeutic Proteins: Strategies to Modulate Their Plasma Half-Lives; Contents; Preface; List of Contributors; Part One: General Information; 1: Half-Life Modulating Strategies -- An Introduction; 1.1 Therapeutic Proteins; 1.2 Renal Clearance and FcRn-Mediated Recycling; 1.3 Strategies to Modulate Plasma Half-Life; 1.3.1 Strategies to Increase the Hydrodynamic Radius; 1.3.2 Strategies Implementing FcRn-Mediated Recycling; 1.4 Half-Life Extension Strategies Applied to a Bispecific Single-Chain Diabody -- A Case Study; 1.5 Conclusion; References. | |
| 588 | 0 | |a Print version record. | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Protein drugs |x Design. | |
| 650 | 0 | |a Proteins |x Therapeutic use. | |
| 650 | 6 | |a Protéines |x Emploi en thérapeutique. | |
| 650 | 7 | |a Protein drugs |x Design |2 fast | |
| 650 | 7 | |a Proteins |x Therapeutic use |2 fast | |
| 758 | |i has work: |a Therapeutic proteins (Text) |1 https://id.oclc.org/worldcat/entity/E39PCFTXHMYWrMKf4RCc7gg3gq |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |z 9783527328499 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=851166 |z Texto completo |
| 938 | |a EBL - Ebook Library |b EBLB |n EBL851166 | ||
| 994 | |a 92 |b IZTAP | ||