Cargando…
Methods for studying nucleic acid/drug interactions /
"Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs naturally relies on th...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Boca Raton :
CRC Press,
©2012.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000Ma 4500 | ||
|---|---|---|---|
| 001 | EBOOKCENTRAL_ocn775741222 | ||
| 003 | OCoLC | ||
| 005 | 20240329122006.0 | ||
| 006 | m o d | ||
| 007 | cr |n||||||||| | ||
| 008 | 120206s2012 fluaf ob 001 0 eng d | ||
| 010 | |a 2011041491 | ||
| 040 | |a YDXCP |b eng |e pn |c YDXCP |d N$T |d OTZ |d CUS |d COO |d OCLCQ |d UIU |d CRCPR |d OCLCQ |d IDEBK |d CDX |d EBLCP |d DEBSZ |d OCLCQ |d UAB |d STF |d BUF |d OCLCF |d OCLCO |d OCLCQ |d UKMGB |d OCLCO |d WYU |d VT2 |d UWO |d OCLCO |d OCLCA |d YDX |d OCLCA |d TYFRS |d OCLCQ |d OCLCO |d LEAUB |d OCLCQ |d UX1 |d OCLCA |d OCLCO |d OCLCQ |d OCL |d SFB |d OCLCQ |d OCLCO | ||
| 016 | 7 | |a 018389932 |2 Uk | |
| 019 | |a 785337436 |a 817067719 |a 824114193 |a 899154970 |a 1009342260 |a 1067226271 |a 1080588752 |a 1082243869 |a 1110599202 |a 1127929509 | ||
| 020 | |a 1439839743 |q (electronic bk.) | ||
| 020 | |a 9781439839744 |q (electronic bk.) | ||
| 020 | |a 1280122021 | ||
| 020 | |a 9781280122026 | ||
| 020 | |a 9780429063411 |q (e-book ; |q PDF) | ||
| 020 | |a 0429063415 | ||
| 020 | |z 9781439839737 |q (hardback ; |q alk. paper) | ||
| 020 | |z 1439839735 |q (hardback ; |q alk. paper) | ||
| 024 | 7 | |a 10.1201/b11691 |2 doi | |
| 029 | 1 | |a AU@ |b 000050091941 | |
| 029 | 1 | |a AU@ |b 000062623709 | |
| 029 | 1 | |a DEBBG |b BV042795859 | |
| 029 | 1 | |a DEBSZ |b 431076774 | |
| 029 | 1 | |a DEBSZ |b 456490418 | |
| 029 | 1 | |a NZ1 |b 14534154 | |
| 029 | 1 | |a UKMGB |b 018389932 | |
| 029 | 1 | |a AU@ |b 000065155034 | |
| 035 | |a (OCoLC)775741222 |z (OCoLC)785337436 |z (OCoLC)817067719 |z (OCoLC)824114193 |z (OCoLC)899154970 |z (OCoLC)1009342260 |z (OCoLC)1067226271 |z (OCoLC)1080588752 |z (OCoLC)1082243869 |z (OCoLC)1110599202 |z (OCoLC)1127929509 | ||
| 037 | |a TANDF_219663 |b Ingram Content Group | ||
| 050 | 4 | |a QP620 |b .M48 2012 | |
| 060 | 1 | 0 | |a QU 58 |
| 072 | 7 | |a MED |x 071000 |2 bisacsh | |
| 082 | 0 | 4 | |a 615.7/04 |2 23 |
| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Methods for studying nucleic acid/drug interactions / |c [edited by] Meni Wanunu, Yitzhak Tor. |
| 260 | |a Boca Raton : |b CRC Press, |c ©2012. | ||
| 300 | |a 1 online resource (xviii, 373 pages, 16 unnumbered pages of plates) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a "Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs naturally relies on the availability of analytical methods that assess the efficacy and nature of interactions between nucleic acids and their putative ligands. This progress can benefit tremendously from new methods that probe nucleic acid/ligand interactions both rapidly and quantitatively. A variety of novel methods for these studies have emerged in recent years, and Methods for Studying DNA/Drug Interactions highlights new and non-conventional methods for exploring nucleic acid/ligand interactions. Designed to present drug-developing companies with a survey of possible future techniques, the book compares their drawbacks and advantages with respect to commonly used tools. Perhaps more importantly, this book was written to inspire young scientists to continue to advance these methods into fruition, especially in light of current capabilities for assay miniaturization and enhanced sensitivity using microfluidics and nanomaterials"--Provided by publisher. | ||
| 505 | 0 | |a Section 1. Classical techniques -- section 2. Emerging techniques. | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Nucleic acids. | |
| 650 | 0 | |a Binding sites. | |
| 650 | 0 | |a Drug testing |x Methodology. | |
| 650 | 0 | |a Binding sites (Biochemistry) | |
| 650 | 0 | |a Ligands. | |
| 650 | 1 | 2 | |a Nucleic Acids |x drug effects |
| 650 | 2 | 2 | |a Binding Sites |
| 650 | 2 | 2 | |a Drug Discovery |x methods |
| 650 | 2 | 2 | |a Ligands |
| 650 | 2 | 2 | |a Molecular Probe Techniques |
| 650 | 2 | 2 | |a Nucleic Acids |x metabolism |
| 650 | 6 | |a Toxicomanie |x Dépistage |x Méthodologie. | |
| 650 | 6 | |a Sites actifs (Biochimie) | |
| 650 | 6 | |a Ligands. | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Ligands |2 fast | |
| 650 | 7 | |a Binding sites (Biochemistry) |2 fast | |
| 650 | 7 | |a Nucleic acids |2 fast | |
| 700 | 1 | |a Wanunu, Meni. | |
| 700 | 1 | |a Tor, Yitzhak. | |
| 776 | 0 | 8 | |i Print version: |t Methods for studying nucleic acid/drug interactions. |d Boca Raton : CRC Press, ©2012 |z 9781439839737 |w (DLC) 2011041491 |w (OCoLC)756157816 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=826973 |z Texto completo |
| 938 | |a Coutts Information Services |b COUT |n 23931196 | ||
| 938 | |a Taylor & Francis |b TAFR |n CRC0KE11828PDF | ||
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL826973 | ||
| 938 | |a EBSCOhost |b EBSC |n 429875 | ||
| 938 | |a ProQuest MyiLibrary Digital eBook Collection |b IDEB |n 352588 | ||
| 938 | |a Taylor & Francis |b TAFR |n 9780429063411 | ||
| 938 | |a YBP Library Services |b YANK |n 15914803 | ||
| 938 | |a YBP Library Services |b YANK |n 7060395 | ||
| 994 | |a 92 |b IZTAP | ||