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Chemistry of protein and nucleic acid cross-linking and conjugation /

Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Wong, Shan S.
Otros Autores: Jameson, David M.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Boca Raton : CRC Press, 2012.
Edición:2nd ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Ch. 1. Overview of protein conjugation
  • ch. 2. Review of protein and nucleic acid chemistry
  • ch. 3. Reagents targeted to specific functional groups
  • ch. 4. How to design and choose cross-linking reagents
  • ch. 5. Homobifunctional cross-linking reagents
  • ch. 6. Heterobifunctional cross-linkers
  • ch. 7. Multifunctional cross-linking reagents
  • ch. 8. Monofunctional and zero-length cross-linking reagents
  • ch. 9. General approaches for chemical cross-linking
  • ch. 10. Analysis of cross-linked products
  • ch. 11. Applications of chemical cross-linking to the study of biological macromolecules
  • ch. 12. Applications of chemical conjugation in the preparation of immunoconjugates and immunogens
  • ch. 13. Application of chemical conjugation for the preparation of immunotoxins and other drug conjugates for targeting theraputics
  • ch. 14. Application of chemical conjugation to solid-state chemistry.