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Chemistry of protein and nucleic acid cross-linking and conjugation /

Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Wong, Shan S.
Otros Autores: Jameson, David M.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Boca Raton : CRC Press, 2012.
Edición:2nd ed.
Temas:
Acceso en línea:Texto completo

MARC

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245 1 0 |a Chemistry of protein and nucleic acid cross-linking and conjugation /  |c Shan S. Wong, David M. Jameson. 
250 |a 2nd ed. 
260 |a Boca Raton :  |b CRC Press,  |c 2012. 
300 |a 1 online resource (xvii, 602, [2] pages of plates) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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500 |a Revised edition of: Chemistry of protein conjugation and cross-linking. c1991. 
504 |a Includes bibliographical references and index. 
505 0 |6 880-01  |a Ch. 1. Overview of protein conjugation -- ch. 2. Review of protein and nucleic acid chemistry -- ch. 3. Reagents targeted to specific functional groups -- ch. 4. How to design and choose cross-linking reagents -- ch. 5. Homobifunctional cross-linking reagents -- ch. 6. Heterobifunctional cross-linkers -- ch. 7. Multifunctional cross-linking reagents -- ch. 8. Monofunctional and zero-length cross-linking reagents -- ch. 9. General approaches for chemical cross-linking -- ch. 10. Analysis of cross-linked products -- ch. 11. Applications of chemical cross-linking to the study of biological macromolecules -- ch. 12. Applications of chemical conjugation in the preparation of immunoconjugates and immunogens -- ch. 13. Application of chemical conjugation for the preparation of immunotoxins and other drug conjugates for targeting theraputics -- ch. 14. Application of chemical conjugation to solid-state chemistry. 
520 |a Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross-linking reagents, and advances have also been made in the area of biosensors and microarray biochips for the detection and analysis of genes, proteins, and carbohydrates. In addition, developments in physical techniques with unprecedented sensitivit. 
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650 0 |a Proteins  |x Crosslinking. 
650 1 2 |a Proteins  |x chemistry 
650 2 2 |a Cross-Linking Reagents 
650 2 2 |a Immunoconjugates  |x chemistry 
650 2 2 |a Immunoconjugates  |x therapeutic use 
650 2 2 |a Nucleic Acids  |x chemistry 
650 6 |a Protéines  |x Réticulation. 
650 7 |a Proteins  |x Crosslinking  |2 fast 
650 7 |a Konjugiertes System  |2 gnd 
650 7 |a Nucleinsäuren  |2 gnd 
650 7 |a Proteine  |2 gnd 
700 1 |a Jameson, David M. 
700 1 |a Wong, Shan S.  |t Chemistry of protein conjugation and cross-linking. 
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880 0 |6 505-01/(N  |a Front Cover -- Contents -- Preface -- Authors -- Chapter 1: Overview of Protein Conjugation -- Chapter 2: Review of Protein and Nucleic Acid Chemistry -- Chapter 3: Reagents Targeted to Specific Functional Groups -- Chapter 4: How to Design and Choose Cross-Linking Reagents -- Homobifunctional Cross-Linking Reagents -- Chapter 6: Heterobifunctional Cross-Linkers -- Chapter 7: Multifunctional Cross-Linking Reagents -- Chapter 8: Monofunctional and Zero -Length Cross -Linking Reagents -- Chapter 9: General Approaches for Chemical Cross-Linking -- Chapter 10: Analysis of Cross-Linked Products -- Chapter 11: Applications of Chemical Cross-Linking to the Study of Biological Macromolecules -- Chapter 12: Applications of Chemical Conjugation in the Preparation of Immunoconjugates and Immunogens -- Chapter 13: Application of Chemical Conjugation for the Preparation of Immunotoxins and Other Drug Conjugates for Targeting Therapeutics -- Chapter 14: Application of Chemical Conjugation to Solid-State Chemistry -- Appendix Ађ́ёAmino Group-Directed Homobifunctional Cross-Linkers -- Appendix Вђ́ёSulfhydryl Group-Directed Homobifunctional Cross-Linkers -- Appendix Сђ́ёPhenolate- and Imidazolyl-Group-Directed Reagents: Bisdiazonium Precursors -- Appendix Dђ́ёGroup Selective Heterobifunctional Cross-Linkers -- Appendix Еђ́ёPhotoactivatable Heterobifunctional Cross-Linking Reagents -- Back Cover. 
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