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Clinical trial design : Bayesian and frequentist adaptive methods /
There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. nevertheless, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. This bo...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, N.J. :
John Wiley & Sons,
©2012.
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| Colección: | Wiley series in probability and statistics.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Yin, Guosheng, |e author. | |
| 245 | 1 | 0 | |a Clinical trial design : |b Bayesian and frequentist adaptive methods / |c Guosheng Yin. |
| 260 | |a Hoboken, N.J. : |b John Wiley & Sons, |c ©2012. | ||
| 300 | |a 1 online resource (xvii, 336 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 490 | 1 | |a Wiley series in probability and statistics | |
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Matter -- Introduction -- Fundamentals of Clinical Trials -- Frequentist versus Bayesian Statistics -- Phase I Trial Design -- Phase II Trial Design -- Phase III Trial Design -- Adaptive Randomization -- Late-Onset Toxicity -- Drug-Combination Trials -- Targeted Therapy Design -- References -- Author Index -- Subject Index -- Wiley Series in Probability and Statistics. | |
| 504 | |a Includes bibliographical references and indexes. | ||
| 505 | 0 | |a Fundamentals of clinical trials -- Frequentist versus Bayesian statistics -- Phase I trial design -- Phase II trial design -- Phase III trial design -- Adaptive randomization -- Late onset toxicity -- Drug combination trials -- Targeted therapy design. | |
| 520 | |a There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. nevertheless, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. This book provides an overview of the fundamentals of clinical trials, the key terminologies and concepts, and a brief review and comparison on Bayesian and frequentist estimation and inference procedures. From the practical point of view, this book introduces various statistical methods that are commonly. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Clinical trials |x Statistical methods. | |
| 650 | 0 | |a Bayesian statistical decision theory. | |
| 650 | 0 | |a Mathematical statistics. | |
| 650 | 1 | 2 | |a Clinical Trials as Topic |x methods |
| 650 | 2 | 2 | |a Bayes Theorem |
| 650 | 2 | 2 | |a Statistics as Topic |x methods |
| 650 | 6 | |a Études cliniques |x Méthodes statistiques. | |
| 650 | 6 | |a Théorie de la décision bayésienne. | |
| 650 | 6 | |a Théorème de Bayes. | |
| 650 | 7 | |a MEDICAL |x Laboratory Medicine. |2 bisacsh | |
| 650 | 7 | |a Bayesian statistical decision theory |2 fast | |
| 650 | 7 | |a Clinical trials |x Statistical methods |2 fast | |
| 650 | 7 | |a Mathematical statistics |2 fast | |
| 758 | |i has work: |a Clinical Trial Design (Text) |1 https://id.oclc.org/worldcat/entity/E39PCYGmB78YgB7fBMP7wY9cmq |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Yin, Guosheng. |t Clinical trial design. |d Hoboken, N.J. : John Wiley & Sons, ©2012 |z 9780470581711 |w (DLC) 2011033589 |w (OCoLC)746461914 |
| 830 | 0 | |a Wiley series in probability and statistics. | |
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