Clinical trial design : Bayesian and frequentist adaptive methods /
There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. nevertheless, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. This bo...
Clasificación: | Libro Electrónico |
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Autor principal: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Hoboken, N.J. :
John Wiley & Sons,
©2012.
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Colección: | Wiley series in probability and statistics.
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Temas: | |
Acceso en línea: | Texto completo |
Sumario: | There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. nevertheless, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. This book provides an overview of the fundamentals of clinical trials, the key terminologies and concepts, and a brief review and comparison on Bayesian and frequentist estimation and inference procedures. From the practical point of view, this book introduces various statistical methods that are commonly. |
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Descripción Física: | 1 online resource (xvii, 336 pages) : illustrations |
Bibliografía: | Includes bibliographical references and indexes. |
ISBN: | 9781118183335 1118183339 9781118183304 1118183304 |