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Microneedle-mediated Transdermal and Intradermal Drug Delivery.

One of the latest techniques in drug delivery, microneedles are used for administering a wide range of drug substances used to treat various medical conditions. Thorough background information is included providing a history of the field. Various methods used to produce micorneedles are described as...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Donnelly, Ryan F.
Otros Autores: Singh, Thakur Raghu Raj, Morrow, Desmond I. J., Woolfson, A. David
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken : John Wiley & Sons, 2012.
Edición:2nd ed.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Donnelly, Ryan F. 
245 1 0 |a Microneedle-mediated Transdermal and Intradermal Drug Delivery. 
250 |a 2nd ed. 
260 |a Hoboken :  |b John Wiley & Sons,  |c 2012. 
300 |a 1 online resource (212 pages) 
336 |a text  |b txt  |2 rdacontent 
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505 0 |a Microneedle-mediated Transdermal and Intradermal Drug Delivery; Contents; Preface; About the Authors; 1 Transdermal Drug Delivery; 1.1 Genesis of transdermal drug delivery; 1.2 Skin anatomy; 1.2.1 The epidermis; 1.2.2 The stratum corneum; 1.2.3 The dermis; 1.2.4 Skin appendages; 1.3 Routes to percutaneous drug absorption; 1.4 Facilitated transdermal drug delivery; 1.4.1 Cryopneumatic and photopneumatic technologies; 1.4.2 Sonophoresis (low-frequency ultrasound); 1.4.3 Iontophoresis; 1.4.4 Electroporation; 1.4.5 Jet injection; 1.4.6 Microneedles; References. 
505 8 |a 2 Microneedles: Design, Microfabrication and Optimization2.1 Introduction; 2.2 Methods of fabricating microneedles; 2.2.1 Microfabrication of silicon microneedles; 2.2.2 Microfabrication of metal and other types of MNs; 2.2.3 Microfabrication of polymeric microneedles; 2.3 Optimization to MN design for transdermal drug delivery; 2.4 Conclusion; References; 3 Microneedle Applicator Designs for Transdermal Drug Delivery Applications; 3.1 Introduction; 3.2 Considerations of microneedle applicators designs; 3.3 Conclusion; References; 4 Transdermal Delivery Applications; 4.1 Introduction. 
505 8 |a 4.2 Transdermal drug delivery4.2.1 Partition co-efficient between 1 and 3; 4.2.2 A relatively low melting point; 4.2.3 A molecular weight less than 500 Da; 4.2.4 Unionized; 4.3 Modulation of transdermal penetration using microneedles; 4.4 Transdermal delivery using solid microneedles; 4.4.1 Transdermal delivery of low molecular weight compounds (RMM <600 Da) in vitro using solid microneedles; 4.4.2 Transdermal delivery of low molecular weight compounds (RMM <600 Da) in vivo using solid microneedles. 
505 8 |a 4.4.3 Transdermal delivery of high molecular weight compounds (RMM> 600 Da) in vitro using solid microneedles4.4.4 Transdermal delivery of high molecular weight compounds (RMM> 600 Da) in vivo using solid microneedles; 4.5 Transdermal delivery using hollow microneedles; 4.5.1 Transdermal delivery of low molecular weight compounds (RMM <600 Da) in vitro using hollow microneedles; 4.5.2 Transdermal delivery of low molecular weight compounds (RMM <600 Da) in vivo using hollow microneedles. 
505 8 |a 4.5.3 Transdermal delivery of high molecular weight compounds (RMM> 600 Da) in vitro using hollow microneedles4.5.4 Transdermal delivery of high molecular weight compounds (RMM> 600 Da) in vivo using hollow microneedles; 4.6 Transdermal delivery using biodegradable microneedles; 4.6.1 Transdermal delivery of low molecular weight compounds in vitro using biodegradable MN; 4.6.2 Transdermal delivery of low molecular weight compounds in vivo using biodegradable MN; 4.6.3 Transdermal delivery of high molecular weight compounds in vitro using biodegradable MN. 
500 |a 4.6.4 Transdermal delivery of high molecular weight compounds in vivo using biodegradable MN. 
520 |a One of the latest techniques in drug delivery, microneedles are used for administering a wide range of drug substances used to treat various medical conditions. Thorough background information is included providing a history of the field. Various methods used to produce micorneedles are described as well as a snapshot of the future directions within the industry. Written by highly qualified authors, this new text is the only title providing a comprehensive review of microneedle research in the fields of transdermal and intradermal drug delivery. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Microinjections. 
650 0 |a Transdermal medication. 
650 0 |a Drug delivery systems. 
650 2 |a Microinjections 
650 2 |a Administration, Cutaneous 
650 2 |a Drug Delivery Systems 
650 6 |a Micro-injections. 
650 6 |a Médicaments  |x Administration par voie transdermique. 
650 6 |a Systèmes d'administration de médicaments. 
650 7 |a Drug delivery systems  |2 fast 
650 7 |a Microinjections  |2 fast 
650 7 |a Transdermal medication  |2 fast 
700 1 |a Singh, Thakur Raghu Raj. 
700 1 |a Morrow, Desmond I. J. 
700 1 |a Woolfson, A. David. 
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776 0 8 |i Print version:  |a Donnelly, Ryan F.  |t Microneedle-mediated Transdermal and Intradermal Drug Delivery.  |d Hoboken : John Wiley & Sons, ©2012  |z 9780470654897 
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