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Muscle Aging : Inclusion-Body Myositis and Myopathies /

The aging of society is leading to many challenges across all areas of medicine. The problems of muscle aging have led to a rise in the incidence of less common conditions, which though not terminal are debilitating and frequently progressive, and often underdiagnosed or misdiagnosed. Written by a t...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Askanas, Valerie, Engel, W. King
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford : Wiley-Blackwell, 2012.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Ageing of the human neuromuscular system : pathological aspects / W. King Engel and Valerie Askanas
  • Aging of the human neuromuscular system : clinical considerations / W. King Engel and Valerie Askanas
  • Aging of the human neuromuscular system : patient vignettes / W. King Engel, Shalini Mahajan, Valerie Askanas
  • Mitochondrial changes in ageing with particular reference to muscle, and possible clinical consequences / Salvatore DiMauro, Eric Schon, Michio Hirano
  • Protein degradation in ageing cells and mitochondria : relevance to the neuromuscular system / Jenny Ngo and Kelvin Davies
  • Human muscle protein metabolism in relation to exercise and aging : potential therapeutic applications / Micah J. Drummond, Blake B. Rasmussen
  • Pathogenesis of sporadic inclusion-body myositis / Valerie Askanas, W. King Engel, Anna Nogalska
  • Inflammatory and autoimmune features of inclusion-body myositis / Marinos Dalakas
  • Clinical symptoms, physical findings, and diagnostic investigations / Frank Mastaglia
  • Pathologic diagnostic criteria of s-IBM and h-IBMS muscle biopsies / Valerie Askanas and W. King Engel
  • Function and mutations of the GNE gene leading to DMRV/h-IBM, animal models, and potential treatments / May Malicdan, Satoru Noguchi, Ichizo Nishino
  • Clinical and ethnic spectrum, laboratory data, and epidemiology of h-IBM due to GNE mutations / Zohar Argov, Ishizo Nishino, Ikiyo Nonaka
  • Consequences of the h-IBM characteristic GNE mutations on muscle proteins in vivo and in vitro / Aldobrando Broccolini and Massimiliano Mirabella
  • Function and structure of VCP mutations leading to h-IBM / Cezary Wojcik
  • Clinical spectrum, including myopathy, Paget's disease, and fronto-temporal dementia : experimental models of VCP mutations, and potential treatments / Virginia Kimonis
  • Animal models of h-IBM due to VCP mutation / Nisha M. Badders and Paul Taylor.