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|a 10.1002/9781444398311
|b Wiley InterScience
|n http://www3.interscience.wiley.com
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|a UAMI
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|a Muscle Aging :
|b Inclusion-Body Myositis and Myopathies /
|c edited by Valerie Askanas and King Engel.
|
260 |
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|a Oxford :
|b Wiley-Blackwell,
|c 2012.
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|a 1 online resource
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|a Includes bibliographical references and index.
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|a Ageing of the human neuromuscular system : pathological aspects / W. King Engel and Valerie Askanas -- Aging of the human neuromuscular system : clinical considerations / W. King Engel and Valerie Askanas -- Aging of the human neuromuscular system : patient vignettes / W. King Engel, Shalini Mahajan, Valerie Askanas -- Mitochondrial changes in ageing with particular reference to muscle, and possible clinical consequences / Salvatore DiMauro, Eric Schon, Michio Hirano -- Protein degradation in ageing cells and mitochondria : relevance to the neuromuscular system / Jenny Ngo and Kelvin Davies -- Human muscle protein metabolism in relation to exercise and aging : potential therapeutic applications / Micah J. Drummond, Blake B. Rasmussen -- Pathogenesis of sporadic inclusion-body myositis / Valerie Askanas, W. King Engel, Anna Nogalska -- Inflammatory and autoimmune features of inclusion-body myositis / Marinos Dalakas -- Clinical symptoms, physical findings, and diagnostic investigations / Frank Mastaglia -- Pathologic diagnostic criteria of s-IBM and h-IBMS muscle biopsies / Valerie Askanas and W. King Engel -- Function and mutations of the GNE gene leading to DMRV/h-IBM, animal models, and potential treatments / May Malicdan, Satoru Noguchi, Ichizo Nishino -- Clinical and ethnic spectrum, laboratory data, and epidemiology of h-IBM due to GNE mutations / Zohar Argov, Ishizo Nishino, Ikiyo Nonaka -- Consequences of the h-IBM characteristic GNE mutations on muscle proteins in vivo and in vitro / Aldobrando Broccolini and Massimiliano Mirabella -- Function and structure of VCP mutations leading to h-IBM / Cezary Wojcik -- Clinical spectrum, including myopathy, Paget's disease, and fronto-temporal dementia : experimental models of VCP mutations, and potential treatments / Virginia Kimonis -- Animal models of h-IBM due to VCP mutation / Nisha M. Badders and Paul Taylor.
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|a Print version record.
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|a The aging of society is leading to many challenges across all areas of medicine. The problems of muscle aging have led to a rise in the incidence of less common conditions, which though not terminal are debilitating and frequently progressive, and often underdiagnosed or misdiagnosed. Written by a team of international experts, this landmark book will look at the general clinical problems associated with muscle aging before examining inclusion-body myositis and myopathies, a group of the more important diseases of muscle aging. With case vignettes to aid diagnosis to ensure correct management of an illness.
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Aging.
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650 |
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|a Myositis.
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1 |
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|a Myositis, Inclusion Body
|x physiopathology
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2 |
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|a Aging
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|a Myositis
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|a Vieillissement.
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|a Myosite.
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|a MEDICAL
|x Nutrition.
|2 bisacsh
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|a Aging
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|a Myositis
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700 |
1 |
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|a Askanas, Valerie.
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700 |
1 |
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|a Engel, W. King.
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776 |
0 |
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|i Print version:
|t Muscle aging.
|d Oxford : Wiley-Blackwell, 2012
|z 9781405196468
|w (DLC) 2011029718
|w (OCoLC)741999167
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