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Pharmacoepidemiology.
Now in its fifth edition, Pharmacoepidemiology defines the discipline and provides the most comprehensive guidance of any book on the topic. Written by world renowned experts in the field, this valuable text surveys the research designs and sources of data available for pharmacoepidemiologic researc...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Chicester :
John Wiley & Sons,
2011.
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| Edición: | 5th ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Title page; Copyright page; List of Contributors; Preface; Acknowledgements; PART I: Introduction; CHAPTER 1 What is Pharmacoepidemiology?; Definition of pharmacoepidemiology; Historical background; The current drug approval process; Potential contributions of pharmacoepidemiology; CHAPTER 2 Basic Principles of Clinical Pharmacology Relevant to Pharmacoepidemiologic Studies; Introduction; Clinical pharmacology and pharmacoepidemiology; Basics of clinical pharmacology; Pharmacokinetics; Special populations; Pharmacodynamics; Pharmacogenomics; Conclusion.
- CHAPTER 3 Basic Principles of Clinical Epidemiology Relevant to Pharmacoepidemiologic StudiesOverview of the scientific method; Types of errors that one can make in performing a study; Criteria for the causal nature of an association; Epidemiologic study designs; Discussion; Conclusion; CHAPTER 4 Sample Size Considerations for Pharmacoepidemiologic Studies; Introduction; Sample size calculations for cohort studies; Sample size calculations for case-control studies; Sample size calculations for case series; Discussion; CHAPTER 5 When Should One Perform Pharmacoepidemiologic Studies?
- Reasons to perform pharmacoepidemiologic studiesSafety versus risk; Risk tolerance; Conclusion; PART II: The Role of Pharmacoepidemiology in Different Sectors; CHAPTER 6 The Role of Pharmacoepidemiology in the Health-Care System and Academia; The drug approval process; Prescribing practices; Evaluation of patients' use of drugs in the health-care system; Assessment of the quality and outcomes of medication use in populations; Policy analysis; Interventional pharmacoepidemiology; Economic assessment of medication-related issues; The academic medical center.
- Consortia of academic medical center programs for pharmacoepidemiologic researchThe future; CHAPTER 7 The Role of Pharmacoepidemiology in Industry; Introduction; Regulatory and industry focus on risk management and epidemiology; Epidemiology in drug safety evaluation; Epidemiology in evaluation of risk-mitigation interventions; Collaborations in research efforts and drug safety initiatives; Conclusions; CHAPTER 8 The Role of Pharmacoepidemiology in Regulatory Agencies; Introduction; The scope of pharmacoepidemiology throughout the product lifecycle; Integrating data from multiple sources.
- Building capacity and collaboration in pharmacoepidemiologyConclusion; CHAPTER 9 Pharmacoepidemiology and the Law; Introduction; Tort law and product liability lawsuits; The effect of regulation on product liability litigation in the US; Pharmacoepidemiology and contract law; Pharmacoepidemiology and intellectual property law; Conclusion; PART III: Sources of Data for Pharmacoepidemiologic Studies; CHAPTER 10 Postmarketing Spontaneous Pharmacovigilance Reporting Systems; Introduction; Description; Strengths; Limitations; Particular applications; The future.