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The Neurology of AIDS.

Neurological complications of progressive HIV-1 infection remain a common cause of morbidity even during widespread use of antiretroviral therapy (ART). Long-term resistance to ART, drug compliance, untoward drug side effects, a myriad of opportunistic infection, depression and other psychiatric dis...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Gendelman, Howard E.
Otros Autores: Grant, Igor, 1942-, Everall, Ian Paul
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford : Oxford University Press, USA, 2011.
Edición:Third edition.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Contents; Contributors; Interactive Topical Discussion on AIDS Neurology: Past, Present, and Future; SECTION 1 HIV-1 BIOLOGY AND IMMUNOLOGY; 1.1 HIV-1 Biology; 1.2 HIV-1 Immunology; 1.3 Chemokines; 1.4 Viral and Host Genetic Factors; 1.5 Genetic Susceptibilities for NeuroAIDS; SECTION 2 INNATE AND CELLULAR IMMUNITY AND NEUROGENESIS; 2.1 Mononuclear Phagocytes; 2.2 Microglia; 2.3 Astrocytes; 2.4 Adaptive Immunity; 2.5 Vaccines; 2.6 Neurogenesis; SECTION 3 BLOOD-BRAIN BARRIER AND HIV CNS ENTRY; 3.1 Blood-Brain Barrier: Structure and Function.
  • 3.2 Endothelial Cell Biology and HIV-1 Infection3.3 Blood-Brain Barrier during Neuroinflammation; 3.4 Mechanisms of Viral and Cell Entry into the Central Nervous System; 3.5 Monocyte-Macrophages and Viral Central Nervous System Entry; SECTION 4 CELLULAR AND VIRAL NEUROTOXICITY AND ABUSED DRUGS; 4.1 Mononuclear Phagocyte Inflammation and Neurotoxicity; 4.2 Neurotoxicity of HIV-1 Proteins; 4.3 HIV-1 and Tat: Neuropathogenesis and Therapeutic Targets; 4.4 HIV-1 gp120; 4.5 HIV-1 and Cannabinoids; 4.6 HIV-1 and Meth; 4.7 HIV-1 and Opioids; 4.8 HIV-1 and Cocaine; SECTION 5 ANIMAL MODELS.
  • 5.1 Simian Immunodeficiency Virus5. 2 Feline Immunodeficiency Virus; 5.3 Caprine Arthritis Encephalitis Virus and Visna; 5.4 Transgenics; 5.5 Murine Models for NeuroAIDS; 5.6 Simian Immunodeficiency Virus and Opiates; 5.7 SIV and FIV Models of Peripheral Neuropathy; 5.8 Animal Models and Bioimaging; SECTION 6 PERSONAL PERSPECTIVES IN LIVING WITH HIV/AIDS; 6.1 HIV and My Mental Health
  • A Personal Reflection; 6.2 Fear and Loathing in HIV Mental Health Care; 6.3 Memories; 6.4 HIV Dementia: A Patient's Perspective. Living with the Suffering, the Diagnosis, and the Uncertainties.
  • 6.5 My Virus Just Turned Twenty-One: A Woman's Perspective of the Long-term Psychological Impact of Living with HIVSECTION 7 CLINICAL AND PATHOLOGIC MANIFESTATIONS OF DISEASE; 7.1 Perspective on HIV CNS Infections; 7.2 HIV-Associated Neurocognitive Disorders; 7.3 The CNS in Acute and Early Infection; 7.4 HIV-1 Neuropathology; 7.5 Peripheral Neuropathy; 7.6 Spinal Cord Disease; 7.7 Myopathy; 7.8 Aging; 7.9 Addiction; SECTION 8 PATHOGENESIS OF COMORBID CONDITIONS; 8.1 NeuroAIDS as an Inflammatory Disorder; 8.2 Neuronal Injury, White Matter Disease, and Neurotrophic Factors.
  • 8.3 Pathobiology of HIV-related Neuropathies8.4 CNS Comorbidities; 8.5 Opportunistic Infections; 8.6 Progressive Multifocal Leukoencephalopathy; 8.7 Neoplasms; 8.8 Hepatitis C; 8.9 HIV and Psychiatric Comorbidities; SECTION 9 DIAGNOSTICS AND BIOMARKERS; 9.1 Bioimaging; 9.2 Magnetic Resonance Imaging; 9.3 Psychological Evaluations; 9.4 Viral and Cellular Biomarkers during Antiretroviral Therapy; 9.5 Viral Dynamics; 9.6 Viral Clades: Role in HIV Neuropathogenesis; 9.7 Proteomics and Biomarkers; SECTION 10 CHILDREN AND ADOLESCENTS.