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Targets and emerging therapies for schizophrenia /

Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover, many schizophrenia patients fail to respond to current antipsychotics. Integrating chemistry, biology, and pharmacolo...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Albert, Jeffrey S., Wood, Michael W. (Michael William), 1961-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, New Jersey : John Wiley & Sons, ©2012.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Dopaminergic hypothesis of schizophrenia : a historical perspective / Aurelija Jucaite and Svante Nyberg
  • Dopamine D2/D3 partial agonists as antipsychotics / Philip G. Strange
  • D1/D5 dopamine agonists as pharmacotherapy for schizophrenia / Kevin N. Boyd and Richard B. Mailman
  • PDE inhibitors as a novel therapeutic approach for schizophrenia / Judith A. Siuciak and William J. Pitts
  • Glutamatergic synaptic dysregulation in schizophrenia / Joseph T. Coyle, Alo Basu, and Michael Benneyworth
  • Metabotropic glutamate 2/3 receptor agonists and positive allosteric modulators of metabotropic glutamate receptor 2 as novel agents for the treatment of schizophrenia / Gerard J. Marek [and others]
  • AMPA receptor positive modulators / John A. Morrow, John K.F. Maclean, and Craig Jamieson
  • Progress in the exploration and development of GlyT1 inhibitors for schizophrenia / Jeffrey S. Albert and Michael W. Wood
  • Combined dopamine D2 and 5-hydroxytryptamine (5-HT)1a receptor strategies for the treatment of schizophrenia, a pharmacological and chemical perspective / Andrew C. Mccreary, Roelof W. Feenstra, and Caitlin A. Jones
  • 5-HT2C and 5-HT6 receptor targeted emerging approaches in schizophrenia / Sharon Rosenzweig-Lipson [and others]
  • The cholinergic hypothesis : an introduction to the hypothesis and a short history / Joseph I. Friedman, Isabella Kanellopoulou, and Vladan Novakovic
  • À7 nicotinic acetylcholine receptors in the treatment of schizophrenia / Mihály Hajós, and Bruce N. Rogers
  • Muscarinic acetylcholine receptors as novel targets for the development of therapeutics for schizophrenia / Christian C. Felder [and others]
  • Will modulation of neuropeptide receptors produce the next generation of antipsychotic drugs? : a focus on the neurokinin and neurotensin systems / Lee A. Dawson, Paul W. Smith, and Jeannette M. Watson
  • GABA and schizophrenia / John H. Kehne and George D. Maynard.