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Proteomics of biological systems : protein phosphorylation using Mass spectrometry techniques /
Phosphorylation is the addition of a phosphate (PO₄) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine wh...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, N.J. :
John Wiley & Sons,
©2012.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Ham, Bryan M. | |
| 245 | 1 | 0 | |a Proteomics of biological systems : |b protein phosphorylation using Mass spectrometry techniques / |c Bryan M. Ham. |
| 260 | |a Hoboken, N.J. : |b John Wiley & Sons, |c ©2012. | ||
| 300 | |a 1 online resource (xxiii, 350 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 505 | 0 | |a Posttranslational Modification (PTM) of Proteins -- Glycosylation of Proteins -- Sulfation of Proteins as Posttranslational Modification -- Eukaryote PTM as Phosphorylation: Normal State Studies -- Eukaryote PTM as Phosphorylation: Perturbed State Studies -- Prokaryotic Phosphorylation of Serine, Threonine, and Tyrosine -- Prokaryotic Phosphorylation of Histidine -- Appendix I: Atomic Weights and Isotopic Compositions -- Appendix II: Periodic Table of the Elements -- Appendix III: Fundamental Physical Constants. | |
| 520 | |a Phosphorylation is the addition of a phosphate (PO₄) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group. It also provides a combination of detailed, step-by-step methodology for phosphoproteomic sample preparation, mass spectral instrumental analysis, and data interpretation approaches. Furthermore, it includes the use of bioinformatic Internet tools such as the Blast2GO gene ontology (GO) tool, used to help understand and interpret complex data collected in these studies. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 546 | |a English. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Proteomics |x Methodology. | |
| 650 | 0 | |a Phosphorylation |x Research |x Methodology. | |
| 650 | 0 | |a Phosphoproteins |x Synthesis. | |
| 650 | 0 | |a Mass spectrometry. | |
| 650 | 2 | |a Mass Spectrometry | |
| 650 | 6 | |a Protéomique |x Méthodologie. | |
| 650 | 6 | |a Phosphorylation |x Recherche |x Méthodologie. | |
| 650 | 6 | |a Phosphoprotéines |x Synthèse. | |
| 650 | 6 | |a Spectrométrie de masse. | |
| 650 | 6 | |a Systèmes biologiques |x Recherche |x Méthodologie. | |
| 650 | 7 | |a mass spectrometry. |2 aat | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biochemistry. |2 bisacsh | |
| 650 | 7 | |a Mass spectrometry |2 fast | |
| 650 | 7 | |a Phosphoproteins |x Synthesis |2 fast | |
| 655 | 4 | |a Electronic resource. | |
| 758 | |i has work: |a Proteomics of biological systems (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGqJ3mWXm3QVKDmktVcWwC |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Ham, Bryan M. |t Proteomics of Biological Systems. |d Hoboken, NJ : Wiley, ©2012 |z 9781118028964 |w (OCoLC)728656705 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=818767 |z Texto completo |
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