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Peptide drug discovery and development : translational research in academia and industry /

Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the ""bench to bedside"" translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Castanho, Miguel A. R. B., Santos, Nuno
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Weinheim : Wiley-VCH, ©2011.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Matter
  • The Academia-Market Bouncing of Peptide Drugs : Challenges and Strategies in Translational Research with Peptide Drugs. Peptides as Leads for Drug Discovery / Paul J Edwards, Steven R LaPlante
  • Marketing Antimicrobial Peptides: A Critical Academic Point of View / Eduard Bardaj̕
  • Oral Peptide Drug Delivery: Strategies to Overcome Challenges / Josias H Hamman, Jan H Steenekamp
  • Rational Design of Amphipathic a-Helical and Cyclic [beta]- Sheet Antimicrobial Peptides: Specificity and Therapeutic Potential / Wendy J Hartsock, Robert S Hodges
  • Conotoxin-Based Leads in Drug Design / Muharrem Akcan, David J Craik
  • Plant Antimicrobial Peptides: From Basic Structures to Applied Research / Suzana M Ribeiro, Simoni C Dias, Octavio L Franco
  • Peptide Drugs' Translational Tales : Peptide Drugs before, Through and after Industry Pipelines. Omiganan Pentahydrochloride: A Novel, Broad-Spectrum Antimicrobial Peptide for Topical Use / Evelina Rubinchik, Dominique Dugourd
  • Turning Endogenous Peptides into New Analgesics: The Example of Kyotorphin Derivatives / Marta M B Ribeiro, Isa D Serrano, S̤nia S̀ Santos
  • The Development of Romiplostim : A Therapeutic Peptibody Used to Stimulate Platelet Production / Graham Molineux, Ping Wei
  • HIV vs. HIV: Turning HIV-Derived Peptides into Drugs / Henri G Franquelim, Pedro M Matos, A Salom̌ Veiga
  • Sifuvirtide, A Novel HIV-1 Fusion Inhibitor / Xiaobin Zhang, Hao Wu, Fengshan Wang
  • Whither Peptide Drugs? Peptides Shaping the Future of Drug Development. Endogenous Peptides and Their Receptors as Drug Discovery Targets for the Treatment of Metabolic Disease / Mary Ann Pelleymounter, Yuren Wang, Ning Lee
  • Translation of Motilin and Ghrelin Receptor Agonists into Drugs for Gastrointestinal Disorders / Gareth J Sanger, John Broad, David H Alpers
  • Of Mice and Men: Translational Research on Amylin Agonism / Jonathan D Roth, Christine M Mack, James L Trevaskis, David G Parkes
  • Peptides and Polypeptides as Immunomodulators and Their Consequential Therapeutic Effect in Multiple Sclerosis and Other Autoimmune Diseases / Ruth Arnon, Michael Sela, Rina Aharoni
  • Development of Antibody Fragments for Therapeutic Applications / Sofia Carte-Real, Frederico Aires da Silva, Joao Gonzalves
  • Index.