Cargando…
Oral Bioavailability : Basic Principles, Advanced Concepts, and Applications /
Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications is designed to help ch...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, N.J. :
John Wiley & Sons,
©2011.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 a 4500 | ||
|---|---|---|---|
| 001 | EBOOKCENTRAL_ocn746324265 | ||
| 003 | OCoLC | ||
| 005 | 20240329122006.0 | ||
| 006 | m o d | ||
| 007 | cr cn||||||||| | ||
| 008 | 110811s2011 nju ob 000 0 eng d | ||
| 040 | |a DG1 |b eng |e pn |c DG1 |d IDEBK |d YDXCP |d E7B |d OCLCQ |d OCLCO |d OCLCQ |d EBLCP |d N$T |d OCLCF |d OCLCQ |d NLGGC |d OCLCQ |d COO |d OCLCQ |d NKT |d DEBBG |d AZK |d LOA |d OCLCO |d OCLCA |d COCUF |d DG1 |d CHVBK |d OCLCO |d MERER |d OCLCO |d Z5A |d MOR |d LIP |d OCLCO |d DXU |d PIFAG |d ZCU |d OCLCO |d OCLCQ |d MERUC |d OCLCO |d OCLCQ |d OCLCO |d STF |d OCLCO |d OCLCA |d U3W |d OCLCA |d OCLCQ |d WRM |d NRAMU |d ICG |d VT2 |d AU@ |d OCLCO |d OCLCQ |d WYU |d OCLCO |d OCLCA |d TKN |d OCLCO |d OCLCQ |d OCLCO |d BRX |d DKC |d OCLCQ |d UX1 |d OCLCQ |d OCLCA |d OCLCQ |d OCLCO |d UKAHL |d AAA |d OCLCO |d OCL |d OCLCQ |d OCLCO |d OCLCL | ||
| 016 | 7 | |a 101552030 |2 DNLM | |
| 016 | 7 | |a 015886771 |2 Uk | |
| 019 | |a 754329660 |a 769189154 |a 816862072 |a 862970845 |a 961512164 |a 962669172 |a 966107717 |a 988458921 |a 992018835 |a 992866979 |a 1037915437 |a 1038613956 |a 1045468481 |a 1055383958 |a 1062917151 |a 1077279067 |a 1081252574 | ||
| 020 | |a 9781118067598 |q (electronic bk.) | ||
| 020 | |a 1118067592 |q (electronic bk.) | ||
| 020 | |a 9781118067529 |q (electronic bk.) | ||
| 020 | |a 1118067525 |q (electronic bk.) | ||
| 020 | |a 1283257769 | ||
| 020 | |a 9781283257763 | ||
| 020 | |a 9781118067581 | ||
| 020 | |a 1118067584 | ||
| 020 | |z 0470260998 | ||
| 020 | |z 9780470260999 | ||
| 029 | 1 | |a AU@ |b 000047980923 | |
| 029 | 1 | |a AU@ |b 000053280137 | |
| 029 | 1 | |a AU@ |b 000060536314 | |
| 029 | 1 | |a CHNEW |b 000938055 | |
| 029 | 1 | |a CHVBK |b 480183627 | |
| 029 | 1 | |a DEBBG |b BV041049592 | |
| 029 | 1 | |a DEBBG |b BV043393374 | |
| 029 | 1 | |a DEBBG |b BV044154361 | |
| 029 | 1 | |a DEBSZ |b 485004992 | |
| 029 | 1 | |a NZ1 |b 15123121 | |
| 035 | |a (OCoLC)746324265 |z (OCoLC)754329660 |z (OCoLC)769189154 |z (OCoLC)816862072 |z (OCoLC)862970845 |z (OCoLC)961512164 |z (OCoLC)962669172 |z (OCoLC)966107717 |z (OCoLC)988458921 |z (OCoLC)992018835 |z (OCoLC)992866979 |z (OCoLC)1037915437 |z (OCoLC)1038613956 |z (OCoLC)1045468481 |z (OCoLC)1055383958 |z (OCoLC)1062917151 |z (OCoLC)1077279067 |z (OCoLC)1081252574 | ||
| 037 | |a 10.1002/9781118067598 |b Wiley InterScience |n http://www3.interscience.wiley.com | ||
| 050 | 4 | |a RM301.6 |b .O73 2011 | |
| 060 | 4 | |a QV 38 | |
| 072 | 7 | |a MED |x 023000 |2 bisacsh | |
| 072 | 7 | |a MED |x 058170 |2 bisacsh | |
| 072 | 7 | |a MED |x 071000 |2 bisacsh | |
| 072 | 7 | |a MED |x 072000 |2 bisacsh | |
| 072 | 7 | |a MJ |2 bicssc | |
| 082 | 0 | 4 | |a 615/.19 |2 22 |
| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Oral Bioavailability : |b Basic Principles, Advanced Concepts, and Applications / |c edited by Ming Hu, Xiaoling Li. |
| 260 | |a Hoboken, N.J. : |b John Wiley & Sons, |c ©2011. | ||
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 380 | |a Bibliography | ||
| 505 | 0 | |a Frontmatter -- Color Plates -- Barriers to Oral Bioavailability--An Overview / Ming Hu, Xiaoling Li -- Physicochemical Characterization of Pharmaceutical Solids / Smita Debnath -- Solubility of Pharmaceutical Solids / Lauren Wiser, Xiaoling Gao, Bhaskara Jasti, Xiaoling Li -- Dissolution of Pharmaceutical Solids / Josephine L P Soh, Paul W S Heng -- Biological and Physiological Features of the Gastrointestinal Tract Relevant to Oral Drug Absorption / Paul C Ho -- Absorption of Drugs via Passive Diffusion and Carrier-Mediated Pathways / Miki Susanto Park, Jae H Chang --Correlations of Pharmaceutical Dosage Forms / Deliang Zhou, Yihong Qiu -- Drug Metabolism in Gastrointestinal Tract / Rashim Singh, Ming Hu -- Efflux of Drugs via Transporters--The Antiabsorption Pathway / Jae H Chang, James A Uchizono, Miki Susanto Park -- Liver Drug Metabolism / Leslie M Tompkins, Hongbing Wang -- Protein Binding of Drugs / Antonia Kotsiou, Christine Tesseromatis -- Urinary Excretion of Drugs and Drug Reabsorption / Pankaj Gupta, Bo Feng, Jack Cook -- Pharmacokinetic Behaviors of Orally Administered Drugs / Jaime A Yez, Dion R Brocks, Laird M Forrest, Neal M Davies -- Effects of Food on Drug Absorption / Venugopal P Marasanapalle, Xiaoling Li, Bhaskara R Jasti -- Drug₆Drug Interactions and Drug-Dietary Chemical Interactions / Ge Lin, Zhong Zuo, Na Li, Li Zhang -- Anatomical and Physiological Factors Affecting Oral Drug Bioavailability in Rats, Dogs, and Humans / Ayman El-Kattan, Susan Hurst, Joanne Brodfuehrer, Cho-Ming Loi -- Amino Acid Drug Transporters / Zhong Qiu, Ming Hu -- Drug Transporters and Their Role in Absorption and Disposition of Peptides and Peptide-Based Pharmaceuticals / David J Lindley, Stephen M Carl, Dea Herrera-Ruiz, Li F Pan, Lori B Karpes, Jonathan M E Goole, Olafur S Gudmundsson, Gregory T Knipp -- Organic Anion and Cation Drug Transporters / Takashi Sekine, Hiroyuki Kusuhara -- Gastric Retentive Drug Delivery Systems / John R Cardinal, Avinash Nangia -- Lipid-Based and Self-Emulsifying Oral Drug Delivery Systems / Sravan Penchala, Anh-Nhan Pham, Ying Huang, Jeffrey Wang -- Prodrug Strategies to Enhance Oral Drug Absorption / Sai H S Boddu, Deep Kwatra, Ashim K Mitra -- Oral Delivery of Protein/Peptide Therapeutics / Puchun Liu, Steven Dinh -- ABC Transporters in Intestinal and Liver Efflux / Marilyn E Morris, Yash A Gandhi -- Interplay between Efflux Transporters and Metabolic Enzymes / Stephen Wang -- Regulatory Considerations in Metabolism- and Transporter-Based Drug Interactions / Yuanchao (Derek) Zhang, Lei Zhang, John M Strong, Shiew-Mei Huang -- Caco-2 Cell Culture Model for Oral Drug Absorption / Kaustubh Kulkarni, Ming Hu -- MDCK Cells and Other Cell-Culture Models of Oral Drug Absorption / Deep Kwatra, Sai H S Boddu, Ashim K Mitra -- Intestinal Perfusion Methods for Oral Drug Absorptions / Wei Zhu, Eun Ju Jeong -- Liver Perfusion and Primary Hepatocytes for Studying Drug Metabolism and Metabolite Excretion / Cindy Q Xia, Chuang Lu, Suresh K Balani -- Methods for Oral Bioavailability Studies / Ana Ruiz-Garcia, Marival Bermejo -- Determination of Regulation of Drug-Metabolizing Enzymes and Transporters / Bin Zhang, Wen Xie -- Computational and Pharmacoinformatic Approaches to Oral Bioavailability Prediction / Miguel Angel Cabrera-P̌rez, Isabel Gonzalez-alvarez -- Index -- Wiley Series in Drug Discovery and Development. | |
| 504 | |a Includes bibliographical references. | ||
| 520 | |a Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications is designed to help chemists, biologists, life science researchers, pharmaceutical scientists, pharmacologists, clinicians, and graduate and students become familiar with the fundamentals and practices of the science of oral bioavailability. The difference in rate and extent between a drug taken orally and the actual amount of a drug reaching the circulatory system, oral bioavailability is an essential parameter for determining the efficacy and adverse effects of new and developing medications, as well as finding an optimal dosing regimen. This book provides a much-needed one-stop resource to help readers better understand and appreciate the many facets and complex problems of oral bioavailability, including the basic barriers to oral bioavailability, the methods used to determine relevant parameters, and the challenges of drug delivery. In addition, this comprehensive book discusses biological and physicochemical methods for improving bioavailability, integrates physicochemistry with physiology and molecular biology, and includes several state-of-the-art technologies and approaches-Caco-2 cell culture model, MDCK, and other related cell culture models-which are used to study the science of oral bioavailability. | ||
| 588 | 0 | |a Print version record. | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Drugs |x Bioavailability. | |
| 650 | 0 | |a Drug development. | |
| 650 | 0 | |a Intestinal absorption. | |
| 650 | 0 | |a Bioavailability. | |
| 650 | 2 | |a Biological Availability | |
| 650 | 2 | |a Drug Delivery Systems | |
| 650 | 2 | |a Intestinal Absorption | |
| 650 | 6 | |a Médicaments |x Biodisponibilité. | |
| 650 | 6 | |a Médicaments |x Développement. | |
| 650 | 6 | |a Absorption intestinale. | |
| 650 | 6 | |a Biodisponibilité. | |
| 650 | 7 | |a MEDICAL |x Drug Guides. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Nursing |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Pharmacy. |2 bisacsh | |
| 650 | 7 | |a Bioavailability |2 fast | |
| 650 | 7 | |a Drug development |2 fast | |
| 650 | 7 | |a Drugs |x Bioavailability |2 fast | |
| 650 | 7 | |a Intestinal absorption |2 fast | |
| 655 | 4 | |a Electronic resource. | |
| 700 | 1 | |a Hu, Ming, |c Ph. D. |1 https://id.oclc.org/worldcat/entity/E39PCjKrypxTKGy9X8Y6R6pXVC | |
| 700 | 1 | |a Li, Xiaoling, |d 1957- |1 https://id.oclc.org/worldcat/entity/E39PCjC9cDPF7JtxVpdTBhDJfy | |
| 758 | |i has work: |a Oral bioavailability (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGgJD7jgx7kqWBkrw6FYRq |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |t Oral bioavailability. |d Hoboken, N.J. : John Wiley & Sons, ©2011 |z 9780470260999 |w (DLC) 2011002983 |w (OCoLC)664668302 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=693185 |z Texto completo |
| 938 | |a Askews and Holts Library Services |b ASKH |n AH21622828 | ||
| 938 | |a EBL - Ebook Library |b EBLB |n EBL693185 | ||
| 938 | |a ebrary |b EBRY |n ebr10510394 | ||
| 938 | |a EBSCOhost |b EBSC |n 535842 | ||
| 938 | |a ProQuest MyiLibrary Digital eBook Collection |b IDEB |n 325776 | ||
| 938 | |a YBP Library Services |b YANK |n 6985744 | ||
| 938 | |a YBP Library Services |b YANK |n 3588211 | ||
| 938 | |a YBP Library Services |b YANK |n 12669879 | ||
| 994 | |a 92 |b IZTAP | ||