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Applications of toxicogenomics in safety evaluation and risk assessment /
"This book provides a timely overview of toxicogenomics, with special emphasis on the practical applications of this technology to the risk assessment process. Introductory sections are followed by a series of chapters highlighting practical and systematic applications of toxicogenomics in info...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, N.J. :
John Wiley & Sons,
©2011.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Toxicology, "omics" technologies, and toxicogenomics : a primer
- Introduction to human health risk assessment
- Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward
- Approaches and practical considerations for the analysis of toxicogenomics data
- Genomics in identifying mutagenic mode of action in carcinogenesis
- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens
- Genomics in characterizing endocrine toxicity
- Studying organ specific toxicity using gene expression profiling
- Toxicogenomic studies in human populations
- Toxicogenomics applied to ecological risk assessment
- Analysis of transcriptomic dose response data for toxicology and risk assessment
- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges
- Toxicogenomics and animal alternatives
- Toxicogenomics and the regulatory framework
- Standardization of gene expression information for the safety evaluation--activities in Japan
- Applying transcriptional profiling in drug safety evaluation
- Reframing the risk assessment paradigm : towards a systems biology approach.