Development of Vaccines : From Discovery to Clinical Testing /

Development of Vaccines: From Discovery to Clinical Testing outlines the critical steps, and analytical tools and techniques, needed to take a vaccine from discovery through a successful clinical trial. Contributions from leading experts in the critical areas of vaccine expression, purification, for...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Manmohan Singh, 1964 November 8-, Srivasta, Indresh K.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, N.J. : John Wiley & Sons, ©2011.
Temas:
Vaccines.
Drug development.
Drug stability.
Vaccines > pharmacology
Drug Discovery > methods
Drug Stability
Vaccines
Vaccins.
Médicaments > Développement.
Médicaments > Stabilité.
MEDICAL > Pharmacology.
Drug development
Drug stability
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Microbial vaccines design : the reverse vaccinology approach / Roberto Rosini, Michele A. Barocchi, Rino Rappuoli
  • Design and development of recombinant vaccines with viral properties / Gerd Lipowsky, Martin F. Bachmann
  • Tools for vaccine design : prediction and validation of highly immunogenic and conserved class II epitopes, and development of epitope-driven vaccines / Anne S. De Groot [and others]
  • Virus like-particle vaccines advantages and challenges / Ted M. Ross [and others]
  • Design platforms of nanocapsules for human therapeutics or vaccines / Masaaki Kawano [and others]
  • Designing immunogens for vaccine development in reference to HIV / Aemro Kassa [and others].
  • Expression and purification of recombinant proteins for vaccine applications / Carlo Zambonelli, Deeann Martinez-Guzmann, and Indresh K. Srivastava
  • DNA vaccines for infectious diesase / Samuel Stepenson, Manmohan Singh, Indresh K. Srivastava
  • Developing stable cell lines for the production of vaccine antigens / Xiaotian Zhong [and others]
  • Spectroscopy of vaccines / C. Russell Middaugh, Sangeeta B. Joshi
  • Biophysical characterization of protein antigens within vaccine formulations / Padima Malyala, Derek O'Hagan, Manmohan Singh
  • Structural characteristics predict the stability of HIV / Zohar Biron [and others]
  • Selection of optimal adjuvants and product factors that affect vaccine immunogenicity / Wei Wang, Manmohan Singh
  • Lyophilization and stabilization of vaccines / James Chesko [and others]
  • Effect of buffers and stabilizers on vaccine stability and efficacy / Shireesh P. Apte, Sydney Ugwu
  • Selection of final product containers / Luis Baez, Adrian Distler
  • From the lab to the clinic : filing a phase I IND for an investigational vaccine / Kenneth G. Surowitz.

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