Reviews Of Accelerator Science And Technology - Volume 2 : Medical Applications Of Accelerators.

The theme of this volume, "Medical Applications of Accelerators", is of enormous importance to human health and has a deep impact on our society. The invention of particle accelerators in the early 20th century created a whole new world for producing energetic X-rays, electrons, protons, n...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Formato: Electrónico eBook
Idioma:Inglés
Publicado: World Scientific 2009.
Colección:Reviews of accelerator science and technology ; v. 2, 2009
Temas:
Particle accelerators.
Accélérateurs de particules.
Particle accelerators
Electronic resource.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover13;
  • Contents
  • Editorial Preface
  • Physical and Biological Basis of Proton and of Carbon Ion Radiation Therapy and Clinical Outcome Data Herman Suit, Thomas F. Delaney and Alexei Trofimov
  • 1. Introduction
  • 2. Physics
  • 2.1. General considerations
  • 2.2. Need for gantries
  • 2.3. Penumbra
  • 2.4. Heterodensities in the beam path a narrow age range. The tumor(s) would be transplanted
  • 3. Radiation-Biological Considerations
  • 3.1. Slopes of dose8211;response curves
  • 3.2. LET and RBE
  • 3.3. RBE and dose
  • 3.4. OER
  • 4. Clinical Outcome Data
  • 4.1. Chordoma
  • 4.2. Chondrosarcoma
  • 4.3. Uveal melanoma
  • 4.4. Head and neck
  • 4.5. Non-small-cell lung carcinoma
  • 4.6. Hepatocellular carcinoma
  • 4.7. Prostate carcinoma
  • 5. Discussion
  • Acknowledgments
  • References
  • The Production of Radionuclides for Radiotracers in Nuclear Medicine Thomas J. Ruth
  • 1. Introduction
  • 2. Radioisotope/Radionuclide Production
  • 2.1. Specific activity [1, 2]
  • 3. Accelerators
  • 3.1. Development of the linac
  • 3.2. Development of the cyclotron
  • 3.3. Choice of an accelerator
  • 4. Medical Applications
  • 4.1. Historical background [2]
  • 4.2. Radionuclides for imaging
  • 4.3. Radionuclides for therapy
  • 4.4. Radioisotope production rates and yield considerations
  • 4.5. Generators
  • 5. Imaging
  • 5.1. Planar imaging
  • 5.2. Single photon emission computed tomography
  • 5.3. Positron emission tomography
  • 6. Functional Imaging
  • 7. Radiotracer and Chemistry Development
  • 7.1. Radiopharmaceuticals
  • 8. Future Directions
  • References
  • Proton Radiation Therapy in the Hospital Environment: Conception, Development, and Operation of the Initial Hospital-Based Facility James M. Slater, Jerry D. Slater and Andrew J. Wroe
  • 1. Introduction
  • 2. Preparation Phase
  • 3. Developmental Phase
  • 3.1. Accelerator performance and maintenance
  • 4. Clinical Operations
  • 4.1. The central nervous system and the base of the skull (in adults): stereotactic radiosurgery
  • 4.2. Fractionated proton therapy for tumors of the central nervous system
  • 4.3. Diseases of the eye and tumors of the head and neck
  • 4.4. Lung, breast, and liver cancer
  • 4.5. Cancer of the prostate
  • 4.6. Pediatric neoplasms
  • 4.7. Perspective
  • 5. Research Activities
  • 5.1. Research strategies
  • 5.2. Future directions
  • 6. Summary
  • References
  • Microwave Electron Linacs for Oncology David H. Whittum
  • 1. Introduction
  • 1.1. Why is an accelerator structure needed?
  • 1.2. How does an accelerator structure work?
  • 1.3. Circuit-equivalent model for a standing wave accelerator
  • 1.4. Cold test
  • 1.5. Multicell accelerator structures
  • 2. Overview of Oncology Linacs
  • 2.1. Ionizing radiation
  • 2.2. History
  • 2.3. Requirements for radiotherapy
  • 2.4. Modern linacs
  • 3. Biperiodic Accelerator Structures
  • 3.1. Side-coupled biperiodic
  • 3.2. Tuning
  • 3.3. Coupler design
  • 4. Beam Dynamics
  • 4.1. Thermionic emission
  • 4.2. Space charge limit
  • 4.3. Envelope equation
  • 5. High-Power Test
  • 5.1. Magnetron
  • 5.2. Accelerator characterization
  • 6. Summary
  • Acknowledgments
  • References
  • Heavy-Particle Radiotherapy: System Design and Application H. Tsujii, S. Minohara and K. Noda
  • T$

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