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Reviews Of Accelerator Science And Technology - Volume 2 : Medical Applications Of Accelerators.

The theme of this volume, "Medical Applications of Accelerators", is of enormous importance to human health and has a deep impact on our society. The invention of particle accelerators in the early 20th century created a whole new world for producing energetic X-rays, electrons, protons, n...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Formato: Electrónico eBook
Idioma:Inglés
Publicado: World Scientific 2009.
Colección:Reviews of accelerator science and technology ; v. 2, 2009
Temas:
Acceso en línea:Texto completo

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505 0 |a Cover13; -- Contents -- Editorial Preface -- Physical and Biological Basis of Proton and of Carbon Ion Radiation Therapy and Clinical Outcome Data Herman Suit, Thomas F. Delaney and Alexei Trofimov -- 1. Introduction -- 2. Physics -- 2.1. General considerations -- 2.2. Need for gantries -- 2.3. Penumbra -- 2.4. Heterodensities in the beam path a narrow age range. The tumor(s) would be transplanted -- 3. Radiation-Biological Considerations -- 3.1. Slopes of dose8211;response curves -- 3.2. LET and RBE -- 3.3. RBE and dose -- 3.4. OER -- 4. Clinical Outcome Data -- 4.1. Chordoma -- 4.2. Chondrosarcoma -- 4.3. Uveal melanoma -- 4.4. Head and neck -- 4.5. Non-small-cell lung carcinoma -- 4.6. Hepatocellular carcinoma -- 4.7. Prostate carcinoma -- 5. Discussion -- Acknowledgments -- References -- The Production of Radionuclides for Radiotracers in Nuclear Medicine Thomas J. Ruth -- 1. Introduction -- 2. Radioisotope/Radionuclide Production -- 2.1. Specific activity [1, 2] -- 3. Accelerators -- 3.1. Development of the linac -- 3.2. Development of the cyclotron -- 3.3. Choice of an accelerator -- 4. Medical Applications -- 4.1. Historical background [2] -- 4.2. Radionuclides for imaging -- 4.3. Radionuclides for therapy -- 4.4. Radioisotope production rates and yield considerations -- 4.5. Generators -- 5. Imaging -- 5.1. Planar imaging -- 5.2. Single photon emission computed tomography -- 5.3. Positron emission tomography -- 6. Functional Imaging -- 7. Radiotracer and Chemistry Development -- 7.1. Radiopharmaceuticals -- 8. Future Directions -- References -- Proton Radiation Therapy in the Hospital Environment: Conception, Development, and Operation of the Initial Hospital-Based Facility James M. Slater, Jerry D. Slater and Andrew J. Wroe -- 1. Introduction -- 2. Preparation Phase -- 3. Developmental Phase -- 3.1. Accelerator performance and maintenance -- 4. Clinical Operations -- 4.1. The central nervous system and the base of the skull (in adults): stereotactic radiosurgery -- 4.2. Fractionated proton therapy for tumors of the central nervous system -- 4.3. Diseases of the eye and tumors of the head and neck -- 4.4. Lung, breast, and liver cancer -- 4.5. Cancer of the prostate -- 4.6. Pediatric neoplasms -- 4.7. Perspective -- 5. Research Activities -- 5.1. Research strategies -- 5.2. Future directions -- 6. Summary -- References -- Microwave Electron Linacs for Oncology David H. Whittum -- 1. Introduction -- 1.1. Why is an accelerator structure needed? -- 1.2. How does an accelerator structure work? -- 1.3. Circuit-equivalent model for a standing wave accelerator -- 1.4. Cold test -- 1.5. Multicell accelerator structures -- 2. Overview of Oncology Linacs -- 2.1. Ionizing radiation -- 2.2. History -- 2.3. Requirements for radiotherapy -- 2.4. Modern linacs -- 3. Biperiodic Accelerator Structures -- 3.1. Side-coupled biperiodic -- 3.2. Tuning -- 3.3. Coupler design -- 4. Beam Dynamics -- 4.1. Thermionic emission -- 4.2. Space charge limit -- 4.3. Envelope equation -- 5. High-Power Test -- 5.1. Magnetron -- 5.2. Accelerator characterization -- 6. Summary -- Acknowledgments -- References -- Heavy-Particle Radiotherapy: System Design and Application H. Tsujii, S. Minohara and K. Noda -- T$ 
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