Cargando…
Prions in Humans and Animals.
This comprehensive work, aimed at both students and researchers alike, systematically covers all aspects of prion diseases (transmissible spongiform encephalopathies), from their history, microbiology and pathology to their transmissibility and prevention. The book describes diseases such as Creutzf...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin :
Walter de Gruyter,
2006.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Frontmatter; Table of Contents; Abbreviations; 1. Historical Introduction; 2. History of Kuru Research; 3. History of Prion Research; 4. The Physical Nature of the Prion; 5. Folding of the Recombinant Prion Protein; 6. Structural Studies of Prion Proteins; 7. Function of Cellular Prion Protein (PrPC) in Copper Homeostasis and Redox Signaling at the Synapse; 8. The Scarpie Isoform of the Prion Protein PrPSe Compared to the Celluar Isoform PrPC; 9. The Phylogeny of Mammalian and Nonmammalian Prion Proteins; 10. Knockouts and Transgenic Mice in Prion Research.
- 11. Transplantation as a Tool in Prion Research12. Prion Strains; 13. Portrait of Kuru; 14. Portrait of Creutzfeldt-Jakob Disease; 15. Portrait of Variant Creutzfeldt-Jakob Disease; 16. Portrait of Gerstmann-Sträussler-Scheinker Disease; 17. Portrait of Fatal Familial Insomnia and Sporadic Fatal Insomnia; 18. Portrait of Scrapie in Sheep and Goat; 19. Portrait of Bovine Spongiform Encephalopathy in Cattle and Other Ungulates; 20. Portrait of Prion Diseases in Zoo Animals; 21. Portrait of Chronic Wasting Disease in Deer Species; 22. Portrait of Transmissible Mink Encephalopathy.
- 23. Portrait of Transmissible Feline Spongiform Encephalopathy24. Portrait of Experimental BSE in Pigs; 25. Portrait of a Spongiform Encephalopathy in Birds and the Transmissibility of Mammalian Prior Diseases to Birds; 26. Pathology and Genetics of Human Prion Diseases; 27. The Pathology of Prion Diseases in Animals; 28. Pathophysiology of Prion Diseases Following Peripheral Infection; 29. Introduction of Surveillance for Human Prion Diseases; 30. Clinical Findings in Human Prion Diseases; 31. Methods for the Clinical Diagnosis of Human Prion Deseases.
- 32. Introduction to Surveillance for Animal Prion Diseases33. Clinical Findings in Bovine Spongiform Encephalopathy; 34. Clinical Findings in Scrapie; 35. Diagnosis of Bovine Spongiform Encephalopathy by Immunological Methods; 36. Epidemiology and Risk Factors of Creutzfeldt-Jakob Disease; 37. Creutzfeldt-Jakob Disease in Germany; 38. The Epidemiology of Kuru; 39. The Course of the BSE Epidemic
- Retrospective Epidemiological Considerations; 40. The Causes of the BSE Epidemic; 41. The Experimental Transmissibility of Prions and Infectivity Distribution in the Body.
- 42. Iatrogenic and "Natural" Transmissibility of Prion Diseases43. Inactivation in Practice
- Risk Assessment and Validation for Food Gelatin; 44. Chemical Disinfection and Inactivation of Prions; 45. Thermal Inactivation of Prions; 46. Prevention of Prion Diseases in the Production of Medicinal Products, Medical Devices, and Cosmetics; 47. Prevention of the Transmission of Prion Diseases in Healthcare Settings; 48. Precautionary Measures for Autopsies Performed in Cases of Suspected Prion Disease; 49. Prevention of Prion Diseases in Research Laboratories.