Sequence-based classification of select agents : a brighter line /

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"Select Agents are defined in regulations through a list of names of particularly dangerous known bacteria, viruses, toxins, and fungi. However, natural variation and intentional genetic modification blur the boundaries of any discrete Select Agent list based on names. Access to technologies th...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores Corporativos: National Research Council (U.S.). Committee on Scientific Milestones for the Development of a Gene Sequence-Based Classification System for the Oversight of Select Agents, National Research Council (U.S.). Board on Life Sciences
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington, D.C. : National Academies Press, [2010], ©2010.
Temas:
Pathogenic microorganisms.
Microbiological laboratories > United States > Safety measures.
Genetic engineering.
Molecular biology.
Laboratory Techniques and Procedures > standards
Microbiological Techniques > standards
Genetic Engineering
Safety Management > methods
Molecular Biology
Micro-organismes pathogènes.
Microbiologie > Laboratoires > États-Unis > Sécurité > Mesures.
Biologie moléculaire.
Génie génétique.
molecular biology.
SCIENCE > Biotechnology.
Genetic engineering
Microbiological laboratories > Safety measures
Molecular biology
Pathogenic microorganisms
United States
Congress
proceedings (reports)
Conference papers and proceedings
Conference papers and proceedings.
Actes de congrès.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Summary
  • The selected agent regulations
  • Challenges of predicting pathogenicity from sequence
  • A proposal for consideration : sequence-based classification of select agents
  • Committee findings and conclusions
  • Appendix A: Statement of task
  • Appendix B. Committee member and staff biographies
  • Appendix C. HHS and USDA select agents and toxins
  • Appendix D. 2009 workshop agenda
  • Appendix E. Applicability of select agent regulations to issues of synthetic genomics
  • Appendix F. Summary of relevant legislation, regulation, and guidance
  • Appendix G. Influenza A and SARS-CoV
  • Appendix H. Virus-host interactions
  • Appendix I. Botulinum neurotoxin, B. anthracis and variola virus
  • Appendix J. Pathogenicity acquisition
  • Appendix K. Interactions of infectious agents with the host
  • Appendix L. Near-term milestones for consideration
  • Appendix M. Executive order : optimizing the security of biological select agents and toxins in the United States.

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