3D cell-based biosensors in drug discovery programs : microtissue engineering for high throughput screening /

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"This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to co...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Kisaalita, William Ssempa, 1953-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Boca Raton : CRC Press, ©2010.
Temas:
Pharmaceutical biotechnology.
Biosensors.
High throughput screening (Drug development)
Cell culture.
Biosensing Techniques > methods
Cells, Cultured
Drug Discovery
Biosensing Techniques
Biotechnologie pharmaceutique.
Biocapteurs.
Criblage à haut débit (Développement des médicaments)
Cellules > Culture.
MEDICAL > Drug Guides.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
MEDICAL > Nursing > Pharmacology.
Cell culture
Biosensors
Pharmaceutical biotechnology
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Biosensors and bioassays
  • Target-driven drug discovery
  • Comparative transcriptional profiling and proteomics
  • Comparative structure and function
  • Chemical microenvironmental factors
  • Spatial and temporal microenvironmental factors
  • Material physical property and force microenvironmental factors
  • Proteomics as a promising tool in the search for 3D biomarkers
  • Readout present and near future
  • Ready-to-use commercial 3D plates
  • Challenges to adopting 3D cultures in HTS programs
  • Cases for 3D cultures in drug discovery
  • Ideal case study design.

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