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3D cell-based biosensors in drug discovery programs : microtissue engineering for high throughput screening /
"This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to co...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Boca Raton :
CRC Press,
©2010.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Kisaalita, William Ssempa, |d 1953- |1 https://id.oclc.org/worldcat/entity/E39PBJcWxG3gTRgKwFJHJTTT73 | |
| 245 | 1 | 0 | |a 3D cell-based biosensors in drug discovery programs : |b microtissue engineering for high throughput screening / |c William S. Kisaalita. |
| 246 | 3 | |a Three-dimensional cell-based biosensors in drug discovery | |
| 260 | |a Boca Raton : |b CRC Press, |c ©2010. | ||
| 300 | |a 1 online resource (xvii, 386 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 520 | |a "This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher | ||
| 504 | |a Includes bibliographical references and indexes. | ||
| 505 | 0 | |a Biosensors and bioassays -- Target-driven drug discovery -- Comparative transcriptional profiling and proteomics -- Comparative structure and function -- Chemical microenvironmental factors -- Spatial and temporal microenvironmental factors -- Material physical property and force microenvironmental factors -- Proteomics as a promising tool in the search for 3D biomarkers -- Readout present and near future -- Ready-to-use commercial 3D plates -- Challenges to adopting 3D cultures in HTS programs -- Cases for 3D cultures in drug discovery -- Ideal case study design. | |
| 588 | 0 | |a Print version record. | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Pharmaceutical biotechnology. | |
| 650 | 0 | |a Biosensors. | |
| 650 | 0 | |a High throughput screening (Drug development) | |
| 650 | 0 | |a Cell culture. | |
| 650 | 1 | 2 | |a Biosensing Techniques |x methods |
| 650 | 2 | 2 | |a Cells, Cultured |
| 650 | 2 | 2 | |a Drug Discovery |
| 650 | 2 | |a Biosensing Techniques | |
| 650 | 6 | |a Biotechnologie pharmaceutique. | |
| 650 | 6 | |a Biocapteurs. | |
| 650 | 6 | |a Criblage à haut débit (Développement des médicaments) | |
| 650 | 6 | |a Cellules |x Culture. | |
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| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Pharmacy. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Nursing |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Cell culture |2 fast | |
| 650 | 7 | |a Biosensors |2 fast | |
| 650 | 7 | |a High throughput screening (Drug development) |2 fast | |
| 650 | 7 | |a Pharmaceutical biotechnology |2 fast | |
| 758 | |i has work: |a 3D cell-based biosensors in drug discovery programs (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGWgg6Wx3gHcdxXyyMJKv3 |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Kisaalita, William Ssempa, 1953- |t 3D cell-based biosensors in drug discovery programs. |d Boca Raton : CRC Press, ©2010 |z 9781420073492 |w (DLC) 2010018119 |w (OCoLC)540161450 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=565953 |z Texto completo |
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