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Bioconductor case studies /

Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Biocon...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Hahne, Florian
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer, ©2008.
Colección:Use R!
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • The ALL data set
  • R and Bioconductor introduction
  • Processing affymetrix expression data
  • Two color arrays
  • Fold changes, log-ratios, background correction, shrinkage estimation and variance stabilization
  • Easy differential expression
  • Differential expression
  • Annotation and metadata
  • Supervised machine learning
  • Unsupervised machine learning
  • Using graphs for interactome data
  • Graph layout
  • Gene set enrichment analysis
  • Hypergeometric testing used for gene set enrichment analysis
  • Solutions to exercises
  • References
  • Index.