DNA microarray technology and data analysis in cancer research /

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DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Li, Shaoguang
Otros Autores: Li, Dongguang
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore ; Hackensack, NJ : World Scientific, ©2008.
Temas:
Cancer cells > Growth > Regulation.
DNA microarrays.
Diseases.
Methodology.
Research.
Gene expression.
Science.
Nucleic acid hybridization.
Decision making > Mathematical models.
Genetics > Technique.
Physical sciences.
Genetic Phenomena
Disease
Methods
Sequence Analysis
Oligonucleotide Array Sequence Analysis > methods
Oligonucleotide Array Sequence Analysis
Neoplasms
Data Interpretation, Statistical
Research
Gene Expression
Science
Investigative Techniques
Molecular Probe Techniques
Microarray Analysis
Nucleic Acid Hybridization
Decision Support Techniques
Analytical, Diagnostic and Therapeutic Techniques and Equipment
Genetic Techniques
Microchip Analytical Procedures
Natural Science Disciplines
Chemistry Techniques, Analytical
Phenomena and Processes
Disciplines and Occupations
Cellules cancéreuses > Croissance > Régulation.
Puces à ADN.
Maladies.
Méthodologie.
Recherche.
Expression génique.
Sciences.
Acides nucléiques > Hybridation.
Prise de décision > Modèles mathématiques.
Génétique > Technique.
Sciences physiques.
illness.
disease.
methodology.
research (function)
sciences (philosophy)
physical sciences.
science (modern discipline)
MEDICAL > Oncology.
HEALTH & FITNESS > Diseases > Cancer.
Physical sciences
Nucleic acid hybridization
Methodology
Genetics > Technique
Gene expression
Diseases
Decision making > Mathematical models
Cancer cells > Growth > Regulation
DNA microarrays
Acceso en línea:Texto completo
Tabla de Contenidos:
  • ch. 1. DNA microarray technology. 1.1. Experimental procedure. 1.2. Experimental design. 1.3. Quality control. 1.4. Interpretation of DNA microarray data. 1.5. Advantages and disadvantages
  • ch. 2. Applications of DNA microarray technology in cancer research. 2.1. Solid tumors. 2.2. Blood cancers. 2.3. Our DNA microarray study using mouse
  • ch. 3. Current analytical methods of DNA microarray data. 3.1. Experimental design. 3.2. Method. 3.3. Quality control diagnostics. 3.4. Statistical analysis. 3.5. Coefficient of variation analysis
  • ch. 4. A novel method for DNA microarray data analysis : SDL global optimization method. 4.1. Research subjects. 4.2. Experimental design. 4.3. Fold change analysis
  • 4.4. More information on SDL global optimization
  • ch. 5. Applications of the SDL global optimization method in DNA microarray data analysis. 5.1. Leukemia cell line study. 5.2. Analyses of publicly available human microarray data. 5.3. Overall methodology. 5.4. Experimental results. 5.5. Discussion. 5.6. Conclusion
  • ch. 6. General discussion and future directions.

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