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Lead generation approaches in drug discovery /

An integrated overview of modern approaches to lead discovery. Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to im...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Rankovic, Zoran, Morphy, Richard
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, N.J. : John Wiley, ©2010.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Lead generation approaches in drug discovery /  |c [edited by] Zoran Rankovic, Richard Morphy. 
260 |a Hoboken, N.J. :  |b John Wiley,  |c ©2010. 
300 |a 1 online resource (xi, 295 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
505 0 |a Lead discovery : the process / William F. Michne -- High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy -- In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath -- Fragment-based lead discovery / Jeffrey S. Albert -- Design of multitarget ligands / Richard Morphy and Zoran Rankovic -- De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak -- Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann -- Early screening for ADMET properties / Dennis A. Smith -- Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm. 
588 0 |a Print version record. 
520 |a An integrated overview of modern approaches to lead discovery. Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to improve the chances of finding such a compound. Written by leading scientists and established opinion leaders from industry and academia, this book provides an authoritative overview of the field, as well as the theory, practice, and scope, of the principal Lead Generation Approaches in Drug Discovery. 
546 |a English. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Drug development. 
650 0 |a Drugs  |x Design. 
650 0 |a High throughput screening (Drug development) 
650 0 |a Lead. 
650 2 |a Drug Discovery  |x methods 
650 2 |a Lead 
650 2 |a Drug Design 
650 6 |a Médicaments  |x Développement. 
650 6 |a Médicaments  |x Conception. 
650 6 |a Criblage à haut débit (Développement des médicaments) 
650 6 |a Plomb. 
650 7 |a MEDICAL  |x Drug Guides.  |2 bisacsh 
650 7 |a MEDICAL  |x Pharmacology.  |2 bisacsh 
650 7 |a MEDICAL  |x Pharmacy.  |2 bisacsh 
650 7 |a MEDICAL  |x Nursing  |x Pharmacology.  |2 bisacsh 
650 7 |a Lead  |2 fast 
650 7 |a Drug development  |2 fast 
650 7 |a Drugs  |x Design  |2 fast 
650 7 |a High throughput screening (Drug development)  |2 fast 
700 1 |a Rankovic, Zoran. 
700 1 |a Morphy, Richard. 
758 |i has work:  |a Lead generation approaches in drug discovery (Work)  |1 https://id.oclc.org/worldcat/entity/E39PD3MFRJfDKdDWwDxQh49TDy  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |t Lead generation approaches in drug discovery.  |d Hoboken, N.J. : John Wiley, ©2010  |z 9780470257616  |z 047025761X  |w (DLC) 2009040188  |w (OCoLC)435422355 
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