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020 |a 9781849731799  |q (electronic bk.) 
020 |a 1849731799  |q (electronic bk.) 
020 |z 9781849730068 
020 |z 1849730067 
024 7 |a 10.1039/9781849731799  |2 doi 
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037 |a T3280  |b Royal Society of Chemistry  |n http://www.rsc.org/spr 
050 4 |a RM666.M513  |b L36 2010 
060 4 |a QV 297  |b L295s 2010 
072 7 |a MED  |x 071000  |2 bisacsh 
072 7 |a KNXC  |2 bicssc 
072 7 |a PSBT  |2 bicssc 
072 7 |a IND  |2 eflch 
082 0 4 |a 615.2654  |2 22 
049 |a UAMI 
100 1 |a Lansdown, A. B. G.  |q (Alan B. G.)  |1 https://id.oclc.org/worldcat/entity/E39PCjyWJCK83JtPxh7QJHt6PP 
245 1 0 |a Silver in Healthcare :  |b Its Antimicrobial Efficacy and Safety in Use /  |c Alan B.G. Lansdown. 
260 |a Cambridge :  |b Royal Society of Chemistry,  |c 2010. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Issues in toxicology,  |x 1757-7179 
588 0 |a Online resource; title from title screen (viewed on June 15, 2010). 
504 |a Includes bibliographical references and index. 
520 |a A comprehensive account of the history of silver in medicine, its clinical benefits and advantages as a broad spectrum antimicrobial agent.  |b Silver in healthcare has many different facets and since the early concepts of microbiology of the 1880's, has been developed from usage in surgical clips, staples, foil wound dressings and surgical implants, to the widespread and clinically effective antiseptic wound dressings, sutures, catheters, bone and dental implants, and cardiovascular devices of today. From the dawn of human civilisation, silver has had a role of water purification and even now has a role in hospital water systems for control of MRSA and legionnaires disease. Biotechnological advances in recent years have extended the antimicrobial properties of silver into production of hygiene textiles and use in domestic products. Important advances have been made in understanding mechanisms of antimicrobial action of silver, the central importance of ionisation patterns in the presence of body fluids and secretion, and the genetical and molecular profiles of silver resistance. This publication is a comprehensive account of the history of silver in medicine, its clinical benefits and wide advantages as a broad spectrum antimicrobial agent. It is clear from the extensive array of publications in recognised and unofficial press, that many misconceptions and misleading conceptions have been perpetuated, leading to errors in evaluation of the safety of the metal in occupational, domestic and therapeutic situations. The book is unique in that it is the only comprehensive presentation of the toxicology of silver and it identifies the major misconceptions in the safety of silver and interpretation of argyria and argyrosis as central features of silver toxicity. In this book, Dr Lansdown reviews the literature from a clinical and experimental viewpoint, with the benefit of his many years research on silver and experience gained in working with clinicians, healthcare product manufacturers and microbiologists. There is also discussion in the book on the relevance of antimicrobial resistance to silver and deficiencies in present day clinical practice in not evaluating incidences of resistance on a routine basis. The subject matter is presented in a readable fashion and includes reference to use of the metal in such practices as acupuncture and treatment of tropical diseases as practised in some parts of the world, each of which is accompanied by special clinical risk. It is also a collation of current views on the use and efficacy of silver as a broad spectrum antibiotic. The chapters which deal specifically with toxicological aspects of silver in clinical, occupational and environmental issues are central to the book's value. The book is aimed at clinicians, research scientists and product manufacturers and will provide ideas for new research and academic endeavour. It is also essential reading for research students with an interest in metal toxicity and its management in mammalian tissues. 
505 0 |a 9781849730068_Publicity; i_iv; v_vi; vii_viii; ix_xi; xii; 001_008; 009_042; 043_071; 072_091; 092_143; 144_151; 152_163; 164_213; 214_249; 250_255; 256_262. 
546 |a English. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Silver  |x Therapeutic use. 
650 0 |a Metals in medicine. 
650 0 |a Anti-infective agents. 
650 0 |a Heavy metals. 
650 0 |a Regeneration (Biology) 
650 0 |a Wound healing. 
650 0 |a Silver. 
650 0 |a Chemical elements. 
650 0 |a Metals. 
650 0 |a Inorganic compounds. 
650 2 |a Anti-Infective Agents 
650 2 |a Transition Elements 
650 2 |a Metals, Heavy 
650 2 |a Regeneration 
650 2 |a Wound Healing 
650 2 |a Anti-Bacterial Agents 
650 2 |a Silver 
650 2 |a Biological Phenomena 
650 2 |a Elements 
650 2 |a Therapeutic Uses 
650 2 |a Metals 
650 2 |a Inorganic Chemicals 
650 2 |a Pharmacologic Actions 
650 2 |a Chemicals and Drugs 
650 2 |a Phenomena and Processes 
650 2 |a Chemical Actions and Uses 
650 6 |a Argent  |x Emploi en thérapeutique. 
650 6 |a Métaux en médecine. 
650 6 |a Antiinfectieux. 
650 6 |a Éléments traces métalliques. 
650 6 |a Régénération (Biologie) 
650 6 |a Cicatrisation. 
650 6 |a Argent. 
650 6 |a Éléments chimiques. 
650 6 |a Métaux. 
650 6 |a Composés inorganiques. 
650 7 |a metal.  |2 aat 
650 7 |a elements (chemical substances)  |2 aat 
650 7 |a Toxicology (non-medical)  |2 bicssc 
650 7 |a MEDICAL  |x Pharmacology.  |2 bisacsh 
650 7 |a Wound healing  |2 fast 
650 7 |a Silver  |2 fast 
650 7 |a Regeneration (Biology)  |2 fast 
650 7 |a Metals  |2 fast 
650 7 |a Inorganic compounds  |2 fast 
650 7 |a Heavy metals  |2 fast 
650 7 |a Chemical elements  |2 fast 
650 7 |a Anti-infective agents  |2 fast 
650 7 |a Metals in medicine  |2 fast 
650 7 |a Silver  |x Therapeutic use  |2 fast 
653 |a Occupational / industrial health & safety. 
653 |a Toxicology (non-medical) 
653 |a Industry. 
758 |i has work:  |a Silver in Healthcare (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCFYvPTQG3WXTmYTVX3PfMd  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |a Lansdown, A.B.G. (Alan B.G.).  |t Silver in healthcare.  |d Cambridge : Royal Society of Chemistry, ©2010  |z 9781849730068  |w (DLC) 2011286412  |w (OCoLC)640076029 
830 0 |a Issues in toxicology. 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=1186089  |z Texto completo 
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