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Biocatalysis for the Pharmaceutical Industry : Discovery, Development, and Manufacturing.
Biocatalysis is rapidly evolving into a key technology for the discovery and production of chemicals, especially in the pharmaceutical industry, where high yielding chemo-, regio-, and enantioselective reactions are critical. Taking the latest breakthroughs in genomics and proteomics into considerat...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken :
John Wiley & Sons,
2009.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- BIOCATALYSIS FOR THE PHARMACEUTICAL INDUSTRY: Discovery, Development, and Manufacturing; Contents; Preface; 1 Enzymes and Their Synthetic Applications: An Overview; 2 Expression Hosts for Enzyme Discovery and Production; 3 Directed Enzyme Evolution and High-Throughput Screening; 4 Applications of Reaction Engineering to Industrial Biotransformations; 5 Chiral Synthesis of Pharmaceutical Intermediates Using Oxynitrilases; 6 Expanding the Scope of Aldolases as Tools for Organic Synthesis; 7 Synthetic Applications of Ketoreductases and Alcohol Oxidases.
- 8 Applications of Nitrile Hydratases and Nitrilases9 Biosynthesis of Drug Metabolites; 10 Application of Whole-Cell Biotransformation in the Pharmaceutical Industry; 11 Combinatorial Biosynthesis of Pharmaceutical Natural Products; 12 Metabolic Engineering for the Development and Manufacturing of Pharmaceuticals; 13 Multimodular Synthases and Supporting Enzymes for Chemical Production; 14 Green Chemistry with Biocatalysis for Production of Pharmaceutic.