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Recombinant Antibodies for Immunotherapy.
This book provides a comprehensive overview of the field of monoclonal antibodies through twenty-five articles by recognized experts in the field.
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Leiden :
Cambridge University Press,
2009.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Half-title; Title; Copyright; Contents; Contributors; Foreword; Preface; RECOMBINANT ANTIBODIES FOR IMMUNOTHERAPY; PART I HUMANIZED ANTIBODIES; CHAPTER ONE Humanization of Recombinant Antibodies; CHAPTER TWO Immunogenicity Assessment of Antibody Therapeutics; CHAPTER THREE In Vitro Screening for Antibody Immunogenicity; PART II GENERATION AND SCREENING OF ANTIBODY LIBRARIES; CHAPTER FOUR Antibody Libraries from Naive V Gene Sources; CHAPTER FIVE Antibodies from IgM Libraries; CHAPTER SIX Generation and Screening of the Synthetic Human Combinatorial Antibody Library HuCAL GOLD.
- PART III TRANSGENIC HUMAN ANTIBODY REPERTOIRESCHAPTER SEVEN Therapeutic Antibodies from XenoMouse Transgenic Mice; CHAPTER EIGHT VelocImmune: Immunoglobulin Variable Region Humanized Mice; PART IV ANTIBODY EFFECTOR FUNCTION; CHAPTER NINE Mechanisms of Tumor Cell Killing by Therapeutic Antibodies; CHAPTER TEN Optimization of Fc Domains to Enhance Antibody Therapeutics; CHAPTER ELEVEN Glycoengineered Therapeutic Antibodies; PART.