Concepts in genetic medicine /

A collection of reviews that highlight the most important issues in the development, manufacture, and commercialization of novel genetic medicines While the field of gene therapy is still a relatively young discipline, it is rapidly evolving and is characterized by impressive scientific and medical...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Dropulic, Boro, Carter, Barrie
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, N.J. : Wiley-Liss, ©2008.
Temas:
Medical genetics.
Gene therapy.
Genetic vectors.
Genetic Therapy > methods
Gene Transfer Techniques
Genetic Vectors
Viruses > genetics
Genetics, Medical
Genetic Therapy
Génétique médicale.
Thérapie génique.
Vecteurs de clonage.
HEALTH & FITNESS > Diseases > Genetic.
MEDICAL > Genetics.
Genetic vectors
Gene therapy
Medical genetics
Review
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover
  • TOC36;CONTENTS
  • CONTRIBUTORS
  • PREFACE
  • INTRODUCTION
  • CH36;1 The Evolution of Human Gene Therapy58; A Journey from Excessive Hype to Excessive Diffidence to Reality
  • VECTOR SYSTEMS
  • CH36;2 Murine Leukemia Virus8211;Based Retroviral Vectors
  • CH36;3 Lentivirus Vectors
  • CH36;4 Adenoviral Vectors58; History and Perspective
  • CH36;5 Adeno45;Associated Virus Vectors
  • CH36;6 SV40 Virus8211;Derived Vectors
  • CH36;7 Herpes Simplex Virus Vectors
  • CH36;8 Nonviral Gene Delivery Systems
  • APPLICATIONS
  • CH36;9 Therapeutic Gene Transfer to Skeletal Muscle
  • CH36;10 Gene Therapy for Cardiovascular Disease
  • CH36;11 Intraarticular Vector Delivery for Inflammatory Joint Disease
  • CH36;12 The Respiratory System as a Platform for Gene Delivery
  • CH36;13 The Brain as a Target for Gene Therapy
  • CH36;14 Immune Responses to Viral Vectors Injected Systemically or into the CNS
  • CH36;15 Cancer Vaccines
  • CH36;16 Genetically Modified T Cells for Human Gene Therapy
  • CH36;17 Lentiviral Vector Delivery of RNAi for the Treatment of HIV45;1 Infection
  • CH36;18 Vector Targeting
  • THE MANUFACTURE OF GENE THERAPY PRODUCTS
  • CH36;19 The Manufacture of Genetic Viral Vector Products
  • CH36;20 The Manufacture of Adeno45;Associated Viral Vectors
  • CH36;21 Lentivirus Vector Manufacturing
  • SAFETY AND REGULATORY CONSIDERATIONS
  • CH36;22 Assays for the Release of Viral Vector Gene Therapy Products for Human Clinical Trials
  • CH36;23 Safety of Retroviral Vectors58; Regulatory and Technical Considerations
  • CH36;24 Assays for the Quality Control of Lentiviral Vectors
  • CH36;25 Assays for Nonviral Vectors
  • CH36;26 Assays for the Release of Cellular Gene Therapy Products
  • CH36;27 Toxicology for Gene Therapy Products58; Concepts and Challenges
  • CH36;28 Regulatory Aspects of Gene Therapy Medicinal Products in the European Union
  • FINANCE AND REIMBURSMENT
  • CH36;29 Venture Capital and Biotechnology Startups
  • CH36;30 The Role of Investment Banking in the Growth of Biotechnology Companies
  • CH36;31 Managing Reimbursement for Gene Therapy Products
  • IDX36;INDEX
  • Last Page.

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