Mammalian cell biotechnology in protein production /

"Hauser and Wagner have presented the new possibilities of Mammalian Cell Biology in a very informative and stimulating manner." Prof. Dr. Hans Fritz, Ludwig-Maximilians-University Munich

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Hauser, Hansjörg, 1949-, Wagner, Roland, 1956-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin ; New York : Walter de Gruyter, 1997.
Temas:
Proteins > Biotechnology.
Animal cell biotechnology.
Mammals > Cytology.
Insect cell biotechnology.
Cell culture.
Recombinant Proteins > genetics
Protein Engineering > methods
Mammals > genetics
Cells, Cultured
Protéines > Biotechnologie.
Cellules > Biotechnologie.
Mammifères > Cytologie.
Cellules > Culture.
SCIENCE > Biotechnology.
Insect cell biotechnology
Cell culture
Animal cell biotechnology
Mammals > Cytology
Proteins > Biotechnology
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 1 Genetic Manipulation of Mammalian Cells
  • 1.1 Hererologous Expression of Genes in Mammalian Cells
  • 1.2 Permanent Gene Expression in Mammalian Cells: Gene Transfer and Selection
  • 1.3 Vectors for Gene Transfer and Expression in Animal Cells
  • 1.4 Aspects of Gene Transfer and Gene Amplification in Recombinant Mammalian Cells
  • 1.5 Isolation of Recombinant Cell Clones Exhibiting High-Level Expression of the Introduced Gene
  • 1.6 Genetic Engineering of Antibodies and Derivatives from Mammalian Cells
  • 1.7 Safety Evaluation of Products Derived From Mammalian Cell Lines
  • 2 Biological Aspects of Animal Cells2.1 Metabolic Control of Animal Cell Culture Processes
  • 2.2 Glycosylation: A Post-Translational Modification
  • 3 Cell Cultivation Technology
  • 3.1 Bioreactors Designed for Animal Cells
  • 3.2 Hydrodynamic Properties in Bioreactors
  • 3.3 Kinetics and Simulation of Animal Cell Processes
  • 3.4 On-line and Off-line Process Analysis
  • 4 Down-Stream Processing
  • 4.1 Principles of Product Extraction from Cell Culture and Purification for Pharmaceutical Proteins
  • 4.2 Validation of Downstream Processes
  • Index

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