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|a 10.1002/9781444318579
|b Wiley InterScience
|n http://www3.interscience.wiley.com
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|a UAMI
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|a Critical pathways to success in CNS drug development /
|c Neal R. Cutler [and others].
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|a Chichester, UK ;
|a Hoboken, NJ :
|b Wiley-Blackwell,
|c 2010.
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300 |
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|a 1 online resource (viii, 263 pages) :
|b illustrations
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
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|a data file
|2 rda
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|a Includes bibliographical references and index.
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|a The impending crisis in CNS drug development -- Animal models and procedures for CNS disorders -- Pre-clinical antecedents to early human clinical trials -- Biomarkers and surrogate markers in drug development -- Neuroimaging and cognitive assessments in early drug development -- Bridging and CSF studies -- A case study from pre-clinical to early clinical trials.
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|a Covering the latest advances in CNS drug development, this book will guide all those involved in pre-clinical to early clinical trials. The authors describe how recent innovations can accelerate the development of novel CNS compounds, improve early detection of efficacy and toxicity signals, and increase the safety of later-stage clinical trials. The current crisis in the drug development industry is critically reviewed, as well as the steps needed to correct the problems, including new government-backed regulations and industry-based innovations designed to accelerate CNS drug development in.
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0 |
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|a Print version record.
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Neuropsychopharmacology.
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650 |
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|a Drug development.
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|a Critical path analysis.
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|a Central nervous system
|x Effect of drugs on
|x Research
|x Methodology.
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|a Central Nervous System Agents
|x pharmacology
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650 |
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|a Clinical Trials as Topic
|x methods
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2 |
|a Drug Evaluation
|x methods
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2 |
2 |
|a Drug Evaluation, Preclinical
|x methods
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|a Neuropsychopharmacologie.
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|a Médicaments
|x Développement.
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|a Méthode du chemin critique.
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|a Système nerveux central
|x Effets des médicaments sur
|x Recherche
|x Méthodologie.
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|
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|a MEDICAL
|x Pain Medicine.
|2 bisacsh
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650 |
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|a MEDICAL
|x Psychiatry
|x Psychopharmacology.
|2 bisacsh
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|a Critical path analysis
|2 fast
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|a Drug development
|2 fast
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|a Neuropsychopharmacology
|2 fast
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700 |
1 |
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|a Cutler, Neal R.
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|i has work:
|a Critical pathways to success in CNS drug development (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCGYhmRbXgV7bwjY3GWhm3P
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
776 |
0 |
8 |
|i Print version:
|t Critical pathways to success in CNS drug development.
|d Chichester, UK ; Hoboken, NJ : Wiley-Blackwell, 2010
|z 9781444330649
|w (DLC) 2009035146
|w (OCoLC)434319490
|
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|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=480427
|z Texto completo
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