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Gene transfer and the ethics of first-in-human research : lost in translation /

"Human gene transfer is widely regarded as one of the most promising technologies for the treatment of a variety of disorders, but it presents practitioners with a variety of difficult ethical questions. Gene Transfer and the Ethics of First-in-Human Research examines the ethical and policy dim...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Kimmelman, Jonathan
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, UK ; New York : Cambridge University Press, 2010.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Introduction: gene transfer lost in translation
  • What is gene transfer?
  • Safety, values, and legitimacy: the protean nature of risk in translational trials
  • Taming uncertainty: risk and gene-transfer clinical research
  • Succor or suckers? Benefit, risk, and the therapeutic misconception
  • Looking backward: a model value for translational trials
  • The chasm: the ethics of initiating first-in-human clinical trials
  • Tropic of cancers: gene transfer in resource-poor settings
  • Great expectations and hard times: expectation management in gene transfer
  • Something in the sight adjusts itself: conclusions.